Azuma Takashi
Graduate School of Pharmaceutical Sciences, Osaka University of Pharmaceutical Sciences.
Yakugaku Zasshi. 2018;138(3):289-296. doi: 10.1248/yakushi.17-00177-4.
Pharmaceuticals are indispensable to contemporary life. Recently, the emerging problem of pharmaceutical-based pollution of river environments, including drinking water sources and lakes, has begun to receive significant attention worldwide. Because pharmaceuticals are designed to perform specific physiological functions in targeted regions of the human body, there is increasing concern regarding their toxic effects, even at low concentrations, on aquatic ecosystems and human health, via residues in drinking water. Pharmaceuticals are consistently employed in hospitals to treat disease; and Japan, one of the most advanced countries in medical treatment, ranks second worldwide in the quantity of pharmaceuticals employed. Therefore, the development of technologies that minimize or lessen the related environmental risks for clinical effluent is an important task as well as that for sewage treatment plants (STPs). However, there has been limited research on clinical effluent, and much remains to be elucidated. In light of this, we are investigating the occurrence of pharmaceuticals, and the development of water treatment systems for clinical effluent. This review discusses the current research on clinical effluent and the development of advanced water treatment systems targeted at hospital effluent, and explores strategies for future environmental risk assessment and risk management.
药物对当代生活不可或缺。最近,河流环境(包括饮用水源和湖泊)受药物污染这一新兴问题已开始在全球范围内受到广泛关注。由于药物旨在在人体的特定部位发挥特定的生理功能,人们越来越担心它们即使在低浓度下,也会通过饮用水中的残留对水生生态系统和人类健康产生毒性影响。医院持续使用药物治疗疾病;日本作为医疗最先进的国家之一,其药物使用量位居世界第二。因此,开发将临床废水相关环境风险降至最低的技术,与污水处理厂面临的任务一样,都是重要任务。然而,关于临床废水的研究有限,仍有许多有待阐明之处。有鉴于此,我们正在研究药物的出现情况以及临床废水处理系统的开发。本综述讨论了当前关于临床废水的研究以及针对医院废水的先进水处理系统的开发,并探讨了未来环境风险评估和风险管理的策略。