[XX male syndrome: a study model of the genetic determination of the male sex].
作者信息
Seboun E, Leroy P, Casanova M, André G, Fellous M
出版信息
Presse Med. 1986 Sep 13;15(29):1355-9.
PMID:2950409
Abstract
Using Y-specific probes, issued from a library of the human Y chromosome, DNA from about 30 XX men has been studied by the Southern technique. Two groups of patients could be distinguished: one with Y genetic material, the second, without Y DNA. Among XX males with Y sequences there was a genetic heterogeneity with a variable amount of Y DNA sequences. These Y DNA sequences come from the short arm of the Y chromosome and are probably translocated to the paternal X. Concerning the other group, in which no Y sequence could be detected, either Y DNA was present but was not detected, or the mechanism of maleness was Y-independent.
摘要
相似文献
1
[XX male syndrome: a study model of the genetic determination of the male sex].
Presse Med. 1986 Sep 13;15(29):1355-9.
2
Highly homologous loci on the X and Y chromosomes are hot-spots for ectopic recombinations leading to XX maleness.X和Y染色体上的高度同源基因座是导致XX男性化的异位重组热点。
Nat Genet. 1994 Jul;7(3):414-9. doi: 10.1038/ng0794-414.
3
The role of the sex-determining region Y gene in the etiology of 46,XX maleness.Y染色体性别决定区基因在46,XX男性化病因学中的作用。
J Clin Endocrinol Metab. 1993 Mar;76(3):690-5. doi: 10.1210/jcem.76.3.8383144.
4
[The Y chromosome and sex determination].[Y染色体与性别决定]
Reprod Nutr Dev. 1990;Suppl 1:27s-38s.
5
Detection of t(X;Y) in 2 XX males using fluorescent in situ hybridization.利用荧光原位杂交技术检测2例XX男性中的t(X;Y)。
Ann Genet. 1995;38(2):102-5.
6
Molecular cytogenetic analysis of XX males using Y-specific DNA sequences, including SRY.使用包括SRY在内的Y特异性DNA序列对XX男性进行分子细胞遗传学分析。
Hum Genet. 1992 Apr;89(1):23-8. doi: 10.1007/BF00207036.
7
Y-specific DNA sequences in male patients with 46,XX and 47,XXX karyotypes.核型为46,XX和47,XXX的男性患者中的Y特异性DNA序列。
Am J Med Genet. 1987 Oct;28(2):393-401. doi: 10.1002/ajmg.1320280218.
8
Human XX males with Y single-copy DNA fragments.携带Y单拷贝DNA片段的人类XX男性。
Nature. 1984;307(5947):172-3. doi: 10.1038/307172a0.
9
Chromosome Y-specific DNA is transferred to the short arm of X chromosome in human XX males.在人类XX男性中，Y染色体特异性DNA转移至X染色体的短臂。
Science. 1986 Aug 15;233(4765):786-8. doi: 10.1126/science.3738510.
10
The human Y chromosome.人类Y染色体。
J Med Genet. 1985 Oct;22(5):329-44. doi: 10.1136/jmg.22.5.329.
Zotero 插件