Wang H R, Lin Y, Zhang X Y, Ma X T
Zhengzhou Hospital of Traditional Chinese Medicine, Zhengzhou, China.
Women and Infants Hospital of Zhengzhou, Zhengzhou, China.
J Biol Regul Homeost Agents. 2018 Jan-Feb;32(1):123-126.
This study aims to assess the value of transvaginal color Doppler sonography (TVCD) combined with colposcopy for diagnosis of early stage cervical cancer and precancerous lesions. From January 2015 to September 2016, one hundred patients, diagnosed as having early stage cervical cancer and precancerous lesions by histopathological study, were selected as the observation subjects. All patients were examined by TVCD and colposcopy, and the results were compared with histopathological findings. The diagnostic accuracy, sensitivity and specificity of TVCD alone, colposcopy alone, and TVCD combined with colposcopy in early stage of cervical cancer and precancerous lesion were compared. The sensitivity, specificity and accuracy of TVCD combined with colposcopy were significantly higher than that of TVCD (P < 0.05), and the sensitivity was significantly higher than that of colposcopy (P < 0.05). The high sensitivity, specificity and accuracy of TVCD combined with colposcopy on the diagnosis of invasive cervical carcinoma (ICC) and cervical intraepithelial neoplasia (CIN) can provide a scientific basis for its use in clinical diagnosis.
本研究旨在评估经阴道彩色多普勒超声检查(TVCD)联合阴道镜检查对早期宫颈癌及癌前病变的诊断价值。选取2015年1月至2016年9月间经组织病理学检查确诊为早期宫颈癌及癌前病变的100例患者作为观察对象。所有患者均接受TVCD及阴道镜检查,并将结果与组织病理学检查结果进行比较。比较TVCD单独检查、阴道镜单独检查以及TVCD联合阴道镜检查对早期宫颈癌及癌前病变的诊断准确性、敏感性和特异性。TVCD联合阴道镜检查的敏感性、特异性和准确性均显著高于TVCD(P<0.05),且敏感性显著高于阴道镜检查(P<0.05)。TVCD联合阴道镜检查对浸润性宫颈癌(ICC)和宫颈上皮内瘤变(CIN)诊断的高敏感性、特异性和准确性可为其临床诊断应用提供科学依据。