Aggarwal Niti R, Bond Rachel M, Mieres Jennifer H
University of Wisconsin, Madison, Wisconsin.
Zucker School of Medicine at Hofstra Northwell, New York.
Clin Cardiol. 2018 Feb;41(2):194-202. doi: 10.1002/clc.22913. Epub 2018 Mar 5.
Substantial advances and insights in medical technology and treatment strategies, and the focus on sex-specific research have contributed to a reduction in cardiovascular mortality in women. Despite these advances, ischemic heart disease (IHD) remains the leading cause of cardiovascular morbidity and mortality of women in the Western world. Advances in cardiovascular imaging, over the past 4 decades, have significantly improved the evaluation and management of the full spectrum of coronary atherosclerosis, which contributes to ischemic heart disease. The development of contemporary and novel diagnostic imaging techniques and tools have assumed an expanded role in the evaluation of symptomatic women to detect not only flow-limiting epicardial coronary stenosis and nonobstructive atherosclerosis, but also ischemia resulting from microvascular dysfunction. IHD is now diagnosed early and with greater accuracy, leading to improved risk assessment and timely therapies in women. In this article, we review the available evidence on the role of contemporary diagnostic imaging techniques in the evaluation of women with suspected IHD.
医学技术和治疗策略取得了重大进展并带来了深刻见解,同时对性别特异性研究的关注促使女性心血管疾病死亡率有所降低。尽管有这些进展,但在西方世界,缺血性心脏病(IHD)仍是女性心血管疾病发病和死亡的主要原因。在过去40年里,心血管成像技术的进步显著改善了对各种冠状动脉粥样硬化的评估和管理,而冠状动脉粥样硬化会导致缺血性心脏病。当代新型诊断成像技术和工具的发展在有症状女性的评估中发挥了更大作用,不仅能检测出导致血流受限的心外膜冠状动脉狭窄和非阻塞性动脉粥样硬化,还能检测出微血管功能障碍导致的缺血。现在IHD能够被早期且更准确地诊断出来,从而改善了对女性的风险评估并实现了及时治疗。在本文中,我们回顾了当代诊断成像技术在疑似IHD女性评估中作用的现有证据。