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成人斯蒂尔病伴显著多浆膜炎。

Adult-onset Still's disease with prominent polyserositis.

作者信息

Farooq Sheikh Ali Sibtain, Marks Jonathan, Hopkinson Neil

机构信息

1 Rheumatology Registrar, Department of Rheumatology, Queen Alexandra Hospital, Portsmouth Hospitals NHS Trust, UK.

2 Consultant Rheumatologist, The Royal Bournemouth & Christchurch Hospitals, UK.

出版信息

Scott Med J. 2018 May;63(2):63-66. doi: 10.1177/0036933018760763. Epub 2018 Mar 5.

Abstract

Adult-onset Still's disease is a systemic autoinflammatory disease the presentation of which can often mimic infection. As a consequence, there is often a delay in diagnosis. Serositis is a recognised but less common clinical feature that can result in complications including cardiac tamponade and constrictive pericarditis. We describe a case of adult-onset Still's disease without the hallmark rash or significant arthritis, presenting with polyserositis that showed a good response to initial steroid treatment and sustained remission with anakinra. An elevated procalcitonin level was due to active adult-onset Still's disease, not bacterial infection.

摘要

成人斯蒂尔病是一种系统性自身炎症性疾病,其表现常常可模仿感染。因此,诊断往往会延迟。浆膜炎是一种已被认识但不太常见的临床特征,可导致包括心脏压塞和缩窄性心包炎在内的并发症。我们描述了一例无典型皮疹或明显关节炎的成人斯蒂尔病病例,该病例以多浆膜炎为表现,对初始类固醇治疗反应良好,并使用阿那白滞素维持缓解。降钙素原水平升高是由于活动性成人斯蒂尔病,而非细菌感染。

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