Department of Orthopedics, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Department of Orthopedics, First Affiliated Hospital of PLA General Hospital, Beijing, People's Republic of China.
Eur Spine J. 2018 Sep;27(9):2303-2311. doi: 10.1007/s00586-018-5514-3. Epub 2018 Mar 5.
Proximal junctional kyphosis (PJK) is a devastating complication for adult spinal deformity (ASD) after correction surgery. However, there is no consensus on the risk factors of PJK, and whether it can be predicted remains unknown. The aim of this study is to detect the primary risk factors for PJK in ASD, and introduce a novel index for prediction of PJK.
Medical records of 62 ASD patients receiving correction surgery from January 2010 to January 2015 were analyzed. Spino-pelvic parameters were evaluated on lateral films before surgery, at 2 weeks' and at follow-up. Primary factors for PJK were evaluated. PJK index was proposed and verified.
Cervical lordosis at follow-up, postoperative C2-C7 SVA, C2-C7 SVA at follow-up, postoperative T1 slope, T1 slope at follow-up, preoperative TLK, LL at follow-up, preoperative PT, postoperative PT, PT at follow-up, preoperative SS, postoperative SS, SS at follow-up, preoperative PT/SS, postoperative PT/SS and PT/SS at follow-up were significantly different between ASD with and without PJK. Adjusted logistic regression analysis showed that preoperative TLK, LL at follow-up, preoperative PT/SS and PT/SS at follow-up were primary factors for PJK. PJK index was defined as 0.160LL at follow-up-0.121preoperative TLK-4.625preoperative PT/SS-3.315PT/SS at follow-up. On the basis of ROC curve, if PJK index was smaller and larger than - 2, the occurrence rate of PJK and non-PJK was 82 and 95%, respectively.
Preoperative TLK, LL at follow-up, preoperative PT/SS and PT/SS at follow-up were primary factors for PJK. PJK index could be used to predict occurrence of PJK effectively. These slides can be retrieved under Electronic Supplementary Material.
矫形手术后近端交界性后凸(PJK)是成人脊柱畸形(ASD)的一种灾难性并发症。然而,对于 PJK 的危险因素尚无共识,其是否可以预测仍不清楚。本研究旨在发现 ASD 中 PJK 的主要危险因素,并引入一种新的 PJK 预测指标。
分析了 2010 年 1 月至 2015 年 1 月期间接受矫形手术的 62 例 ASD 患者的病历。术前、术后 2 周和随访时拍摄侧位片评估脊柱骨盆参数。评估 PJK 的主要因素。提出并验证 PJK 指数。
随访时颈椎前凸角、术后 C2-C7 矢状垂直距离、随访时 C2-C7 矢状垂直距离、术后 T1 斜率、随访时 T1 斜率、术前 TLK、随访时 LL、术前 PT、术后 PT、随访时 PT、术前 SS、术后 SS、随访时 SS、术前 PT/SS、术后 PT/SS 和随访时 PT/SS 在伴和不伴 PJK 的 ASD 患者之间差异有统计学意义。调整后的逻辑回归分析显示,术前 TLK、随访时 LL、术前 PT/SS 和随访时 PT/SS 是 PJK 的主要因素。PJK 指数定义为 0.160LL 随访时-0.121术前 TLK-4.625术前 PT/SS-3.315PT/SS 随访时。基于 ROC 曲线,如果 PJK 指数小于和大于-2,则 PJK 和非 PJK 的发生率分别为 82%和 95%。
术前 TLK、随访时 LL、术前 PT/SS 和随访时 PT/SS 是 PJK 的主要因素。PJK 指数可有效预测 PJK 的发生。这些幻灯片可以在电子补充材料中检索到。