• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

百万分之一的机会:利他主义与骨髓登记。

One Chance in a Million: Altruism and the Bone Marrow Registry.

机构信息

Department of Economics, University of California Santa Barbara, Santa Barbara, CA.

Wesleyan University, Middletown, CT.

出版信息

Am Econ Rev. 2009 Sep;99(4):1309-34. doi: 10.1257/aer.99.4.1309.

DOI:10.1257/aer.99.4.1309
PMID:29508972
Abstract

Stem cell transplants save lives of many patients with blood diseases. Donation is painful, but rarely has lasting adverse effects. Patients can accept transplants only from donors with compatible immune systems. Those lacking a sibling match must seek donations from the general population. The probability that two unrelated persons are compatible is less than 1/10,000. Health authorities maintain a registry of several million genetically tested potential donors who agree to donate if asked. We find that the benefits of adding registrants of every race exceed costs. We also explore the peculiar structure of voluntary public good provision that faces potential donors.

摘要

干细胞移植挽救了许多血液疾病患者的生命。捐献过程虽然痛苦,但很少会产生持久的不良反应。患者只能接受免疫系统相匹配的捐献者的移植。那些没有兄弟姐妹匹配的患者必须从普通人群中寻找捐献者。两个无关个体相匹配的概率小于万分之一。卫生部门维护着一个登记册,其中包含数百万名经过基因测试的潜在捐献者,他们同意在被要求时进行捐献。我们发现,增加每个种族的登记人数所带来的收益超过了成本。我们还探讨了面临潜在捐献者的自愿公共品提供的特殊结构。

相似文献

1
One Chance in a Million: Altruism and the Bone Marrow Registry.百万分之一的机会:利他主义与骨髓登记。
Am Econ Rev. 2009 Sep;99(4):1309-34. doi: 10.1257/aer.99.4.1309.
2
Progress in availability of donors of color: the National Marrow Donor Program.有色人种供体可及性方面的进展:国家骨髓捐献计划
Transplant Proc. 1997 Dec;29(8):3760-5. doi: 10.1016/s0041-1345(97)01102-0.
3
Racial differences in motivators and barriers to blood donation among blood donors.献血者中献血动机和障碍的种族差异。
Arch Pathol Lab Med. 2009 Sep;133(9):1444-7. doi: 10.5858/133.9.1444.
4
Understanding donors' motivations: a study of unrelated bone marrow donors.理解捐赠者的动机:一项关于非亲属骨髓捐赠者的研究
Soc Sci Med. 1997 Jul;45(1):137-47. doi: 10.1016/s0277-9536(96)00327-9.
5
[10 years Swiss bone marrow donor registry].[瑞士骨髓捐献者登记处10年]
Schweiz Med Wochenschr. 1998 Oct 17;128(42):1602-4.
6
Organ transplantation and donation: why minority groups need more organs but donate less-it's complex!器官移植与捐赠:为何少数群体需要更多器官却捐赠更少——情况很复杂!
Crit Care Med. 2014 Jun;42(6):1546-8. doi: 10.1097/CCM.0000000000000264.
7
Regional Differences Among Bone Marrow Registrants: The Results of a Cross-Sectional Telephone-Based Survey.骨髓捐献者的地域差异:基于横断面电话调查的结果。
Transplant Proc. 2021 Mar;53(2):724-729. doi: 10.1016/j.transproceed.2021.01.029. Epub 2021 Feb 10.
8
Perceptions about organ donation among African American, Hispanic, and white high school students.非裔美国学生、西班牙裔学生和白人高中生对器官捐献的看法。
Qual Health Res. 2012 Jul;22(7):921-33. doi: 10.1177/1049732312439631. Epub 2012 Mar 6.
9
Attitudes and physical condition of unrelated bone marrow donors immediately after donation.非亲缘骨髓捐献者在捐献后即刻的态度和身体状况。
Transfusion. 1989 May;29(4):317-22. doi: 10.1046/j.1537-2995.1989.29489242797.x.
10
Searching for HLA-DRB1*1206 in volunteer marrow donors in four US population groups.在美国四个群体的志愿骨髓捐献者中寻找HLA-DRB1*1206。
Tissue Antigens. 2006 Nov;68(5):439-41. doi: 10.1111/j.1399-0039.2006.00689.x.

引用本文的文献

1
Social preferences or sacred values? Theory and evidence of deontological motivations.社会偏好还是神圣价值观?道义动机的理论与证据
Sci Adv. 2022 May 13;8(19):eabb3925. doi: 10.1126/sciadv.abb3925.
2
Estimating HLA haplotype frequencies from homozygous individuals - A Technical Report.从纯合个体估计 HLA 单倍型频率-技术报告。
Int J Immunogenet. 2021 Dec;48(6):490-495. doi: 10.1111/iji.12553. Epub 2021 Sep 27.
3
How Ancestry Influences the Chances of Finding Unrelated Donors: An Investigation in Admixed Brazilians.血统如何影响找到无关供体的机会:混合巴西人的调查。
Front Immunol. 2020 Nov 6;11:584950. doi: 10.3389/fimmu.2020.584950. eCollection 2020.
4
Ethical challenges regarding the use of stem cells: interviews with researchers from Saudi Arabia.关于干细胞使用的伦理挑战:对来自沙特阿拉伯的研究人员的访谈。
BMC Med Ethics. 2020 May 12;21(1):35. doi: 10.1186/s12910-020-00482-6.
5
Immunogenetics in stem cell donor registry work: The DKMS example (Part 1).干细胞供者登记工作中的免疫遗传学:DKMS 范例(第 1 部分)。
Int J Immunogenet. 2020 Feb;47(1):13-23. doi: 10.1111/iji.12471. Epub 2020 Jan 6.
6
Psychology of personal data donation.个人数据捐赠的心理学。
PLoS One. 2019 Nov 20;14(11):e0224240. doi: 10.1371/journal.pone.0224240. eCollection 2019.
7
The degree of major histocompatibility complex matching between purebred Maltese and mongrel dogs using microsatellite markers.使用微卫星标记评估纯种马尔济斯犬和杂种犬之间主要组织相容性复合体的匹配程度。
J Vet Sci. 2019 Mar;20(2):e5. doi: 10.4142/jvs.2019.20.e5. Epub 2019 Mar 7.
8
Simulation shows that HLA-matched stem cell donors can remain unidentified in donor searches.模拟显示,在供体搜索中,与HLA匹配的干细胞供体可能仍然无法确定身份。
Sci Rep. 2016 Feb 15;6:21149. doi: 10.1038/srep21149.
9
Genetic Diversity and Societally Important Disparities.遗传多样性与具有社会重要性的差异
Genetics. 2015 Sep;201(1):1-12. doi: 10.1534/genetics.115.176750.
10
Toward an optimal global stem cell donor recruitment strategy.迈向最优的全球干细胞供体招募策略。
PLoS One. 2014 Jan 30;9(1):e86605. doi: 10.1371/journal.pone.0086605. eCollection 2014.