Gaba S, Didier C, Cohendy R, Préfaut C
C R Seances Soc Biol Fil. 1986;180(5):568-73.
ATP induced-vasodilation was studied using Striadyne, on pulmonary and systemic arterial bed on 10 patients with stable chronic obstructive pulmonary disease. Such significant effects varied according to the dose: pulmonary vasodilation reached maximal level during low rate infusion (2 mumoles/kg/20 min) and systemic vasodilation was related to the dose. The latter became dominant at maximal dose (5 mumoles/kg/20 min). Simultaneously, on four patients, circulating blood level of ATP was assessed. It increased in proportion with the infusion rate and reached respectively 167% and 149 of baseline level on arterial and mixed venous blood.
使用斯特雷迪恩（Striadyne）对10例稳定期慢性阻塞性肺疾病患者的肺和体动脉床进行了ATP诱导的血管舒张研究。这种显著效果因剂量而异：肺血管舒张在低速率输注（2微摩尔/千克/20分钟）时达到最大水平，而体循环血管舒张与剂量有关。后者在最大剂量（5微摩尔/千克/20分钟）时占主导地位。同时，对4例患者评估了ATP的循环血液水平。其随输注速率成比例增加，动脉血和混合静脉血中的水平分别达到基线水平的167%和149%。
