胰岛素增强降压灵的降压作用。
Potentiation of hypotensive effect of debrisoquine by insulin.
作者信息
Hume L
出版信息
Diabet Med. 1985 Sep;2(5):390-1. doi: 10.1111/j.1464-5491.1985.tb00659.x.
Abstract
A 36-year-old man who had been an insulin-dependent diabetic for 27 years developed severe postural hypotension only when taking debrisoquine and a short-acting insulin. Hourly recordings of lying and standing blood pressure after an oral dose of debrisoquine in the presence and absence of short-acting insulin confirmed an interaction between the drugs causing symptoms of postural hypotension which may be confused with hypoglycaemia.
摘要
一名36岁男性，患胰岛素依赖型糖尿病27年，仅在服用异喹胍和短效胰岛素时出现严重体位性低血压。在服用异喹胍后，无论有无短效胰岛素，每小时记录卧位和立位血压，证实这两种药物之间存在相互作用，可引起体位性低血压症状，这些症状可能与低血糖混淆。
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