降压嗪与胍乙啶治疗高血压的比较。
Comparison of debrisoquine and guanethidine in treatment of hypertension.
作者信息
Adi F C, Eze C J, Anwunah A
出版信息
Br Med J. 1975 Mar 1;1(5956):482-5. doi: 10.1136/bmj.1.5956.482.
Abstract
A cross-over trail of debrisoquine and guanethidine in 32 patients showed that both drugs were equally effective in lowering both systolic and diastolic blood pressure. The degree to which they were tolerated by the patients, however, differed greatly. After three months on each drug 18 patients preferred debrisoquine, nine preferred guanethidine, and five showed no particular preference. At current prices the cost of daily treatment to the patient was cheaper with debrisoquine than with guanethidine.
摘要
一项针对32名患者的异喹胍和胍乙啶交叉试验表明，两种药物在降低收缩压和舒张压方面同样有效。然而，患者对它们的耐受程度差异很大。在服用每种药物三个月后，18名患者更喜欢异喹胍，9名更喜欢胍乙啶，5名没有特别偏好。按照目前的价格，患者每日服用异喹胍的治疗费用比服用胍乙啶便宜。
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