Department of Endocrinology, Beijing Jishuitan Hospital, Beijing, China.
Department of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, China.
Diabet Med. 2018 Jun;35(6):721-728. doi: 10.1111/dme.13616. Epub 2018 Mar 30.
To examine whether the age profile of people with Type 1 diabetes differs from that of the general population and in what manner, and to study the clinical characteristics related to metabolic disorders among people with Type 1 diabetes in China.
We sequentially enrolled 849 people with Type 1 diabetes from hospital records review, inpatient wards and outpatient clinics. Data were collected via face-to-face interviews, medical records and venous blood samples. Beijing census data for 2011 were used to provide the general population statistics. Descriptive analysis of the results and tests for differences were performed.
The median (interquartile range) age at diagnosis of diabetes was 16 (9-28) years and the duration of diabetes was 4 (1-8) years. The mean ± sd HbA concentration was 76±28 mmol/mol (9.1±2.5%). Compared with the general population, the population with Type 1 diabetes comprised more young individuals and fewer elderly individuals. The overall prevalence of metabolic syndrome among those with Type 1 diabetes was 10.1% (95% CI 7.9-12.2). People with metabolic syndrome were older and were diagnosed with diabetes at an older age. Hypertension and dyslipidaemia were more common in obese individuals with Type 1 diabetes than in their non-obese counterparts.
Compared with the general population, people with Type 1 diabetes comprised more young and fewer elderly individuals. The prevalence of metabolic syndrome in the Type 1 diabetes population was 10.1%. Hypertension and dyslipidaemia were more prevalent in obese than non-obese individuals.
探讨 1 型糖尿病患者的年龄分布与一般人群有何不同，以及中国 1 型糖尿病患者的代谢紊乱相关临床特征。
我们连续纳入 849 例来自医院病历回顾、住院病房和门诊的 1 型糖尿病患者。通过面对面访谈、病历和静脉血样收集数据。使用 2011 年北京人口普查数据提供一般人群统计数据。对结果进行描述性分析和差异检验。
糖尿病诊断时的中位（四分位距）年龄为 16（9-28）岁，糖尿病病程为 4（1-8）年。平均±标准差 HbA 浓度为 76±28mmol/mol（9.1±2.5%）。与一般人群相比，1 型糖尿病患者中年轻人更多，老年人更少。1 型糖尿病患者代谢综合征的总体患病率为 10.1%（95%CI 7.9-12.2）。患有代谢综合征的患者年龄更大，且诊断糖尿病的年龄更大。1 型糖尿病肥胖患者中高血压和血脂异常比非肥胖患者更常见。
与一般人群相比，1 型糖尿病患者中年轻人更多，老年人更少。1 型糖尿病患者代谢综合征的患病率为 10.1%。与非肥胖患者相比，肥胖患者中高血压和血脂异常更常见。
