Moulis G, Lapeyre-Mestre M
Service de médecine interne, CHU de Toulouse, CHU Purpan, salle Le Tallec, pavillon URM, place du Dr-Baylac, TSA 40031, 31059 Toulouse cedex 9, France; UMR 1027 Inserm-université de Toulouse, faculté de Médecine, 37, allées Jules Guesde, 31000 Toulouse, France; CIC 1436, CHU de Toulouse, CHU Purpan, pavillon PPR, place du Dr-Baylac, TSA 4003, 31059 Toulouse cedex 9, France.
UMR 1027 Inserm-université de Toulouse, faculté de Médecine, 37, allées Jules Guesde, 31000 Toulouse, France; CIC 1436, CHU de Toulouse, CHU Purpan, pavillon PPR, place du Dr-Baylac, TSA 4003, 31059 Toulouse cedex 9, France; Service de pharmacologie médicale et clinique, CHU de Toulouse, Faculté de Médecine, 37, allées Jules Guesde, 31000 Toulouse, France.
Rev Med Interne. 2018 Oct;39(10):805-812. doi: 10.1016/j.revmed.2018.02.012. Epub 2018 Mar 4.
Propensity scores have been proposed in the early 1980s, and are increasingly used in epidemiology since the 2000s. They are is used to minimize the selection bias in observational studies, leading to a comparability between the exposure groups close to that observed in randomized trials. However, they have important limitations. Besides, new statistical techniques to improve the propensity score performances are more and more complex, while the build and the use of propensity score require a strict methodology to avoid bias, imprecision and non-reproducibility. This overview, designed for clinicians, is aimed at describing the advantages, techniques of use and limitations of propensity scores. A reading grid is provided in order to help interpreting studies using propensity scores.
倾向得分在20世纪80年代初被提出，自21世纪以来在流行病学中越来越多地被使用。它们用于最大限度地减少观察性研究中的选择偏倚，使暴露组之间的可比性接近随机试验中的观察结果。然而，它们有重要的局限性。此外，提高倾向得分性能的新统计技术越来越复杂，而倾向得分的构建和使用需要严格的方法来避免偏差、不精确性和不可重复性。本综述专为临床医生设计，旨在描述倾向得分的优点、使用技术和局限性。提供了一个阅读框架，以帮助解释使用倾向得分的研究。
