外用伊维菌素：支持酒渣鼻双重作用模式的数据。
Topical Ivermectin: Data Supporting Dual Modes of Action in Rosacea.
作者信息
Del Rosso James Q
机构信息
Dr. Del Rosso is Research Director at JDR Dermatology Research in Las Vegas, Nevada; Adjunct Clinical Professor of Dermatology at Touro University Nevada, Las Vegas; and with Dermatology and Cutaneous Surgery at Thomas Dermatology in Las Vegas, Nevada.
出版信息
J Clin Aesthet Dermatol. 2017 Sep;10(9):39-42. Epub 2017 Sep 1.
Abstract
Until recently, the potential modes of action of topical ivermectin in rosacea have been speculated but not studied. Short-term studies (12 week), long-term studies (up to 52 weeks), and case report series have now been completed, and topical ivermectin (IVM), formulated as a 1% cream that is applied once daily, has been shown to be effective, well-tolerated, and safe for the treatment of rosacea. This article reviews outcomes from studies that support dual modes of action, including both anti-inflammatory and anti-parasitic effects.
摘要
直到最近，外用伊维菌素治疗酒渣鼻的潜在作用方式一直是推测性的，尚未得到研究。目前，短期研究（12周）、长期研究（长达52周）以及病例报告系列均已完成，外用伊维菌素（IVM）制成1%乳膏，每天涂抹一次，已被证明对治疗酒渣鼻有效、耐受性良好且安全。本文综述了支持双重作用方式的研究结果，包括抗炎和抗寄生虫作用。
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