骨肿瘤患者经外周静脉穿刺中心静脉置管感染的风险分析

Risk analysis on infection caused by peripherally inserted central catheter for bone tumor patients.

作者信息

He Kui, Wan Yongxian, Xian Shengping

机构信息

Department of Bone and Joint Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

Department of Intervention Therapy, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

出版信息

J Cancer Res Ther. 2018 Jan;14(1):90-93. doi: 10.4103/jcrt.JCRT_777_17.

DOI:10.4103/jcrt.JCRT_777_17

PMID:29516966

Abstract

OBJECTIVE

The aim of this study is to explore the related factors affecting infection risk caused by peripherally inserted central catheter (PICC) for bone tumor patients.

METHOD

A retrospective analysis was performed for 223 bone tumor patients who received PICC and were admitted to our hospital from 2004 to 2017. A total of 18 cases (infection group) with PICC catheter-related infections and 205 cases without infection (noninfection group) were studied. First, factor analysis of variance or Chi-square test was applied to compare independent risk factors for PICC catheter-related infections, between bone tumor patients with catheter-related infections and those without catheter-related infections.

RESULTS

This retrospective analysis involved a total of 18 patients with PICC infections and 205 patients without infections. The infection rate was 8.07%. Factor analysis of variance showed that many factors were related to PICC catheter-related infections, including experience of operator (χ = 3.48, P < 0.05), catheter retention time (χ = 7.478, P < 0.05), receiving chemotherapy or not (χ = 2.43, P < 0.05), Karnofsky Performance Scale scores (χ = 2.19, P < 0.05) and the frequency of replacing pad pasting on the point of puncture (χ = 2.23). Logistic regression analysis showed that PICC catheter retention time (odds ratio [OR] = 4.21, P < 0.05) and operator experience (OR = 2.80, P < 0.05) were independent factors affected PICC catheter-related infections.

CONCLUSION

Catheter-related infections were related to experience of PICC operatorand length of catheter retention time.

摘要

目的

本研究旨在探讨影响骨肿瘤患者经外周静脉穿刺中心静脉置管（PICC）感染风险的相关因素。

方法

对2004年至2017年在我院接受PICC置管的223例骨肿瘤患者进行回顾性分析。共研究了18例发生PICC导管相关感染的患者（感染组）和205例未发生感染的患者（非感染组）。首先，应用方差分析或卡方检验比较发生导管相关感染的骨肿瘤患者与未发生导管相关感染的骨肿瘤患者PICC导管相关感染的独立危险因素。

结果

本回顾性分析共纳入18例PICC感染患者和205例未感染患者。感染率为8.07%。方差分析显示，许多因素与PICC导管相关感染有关，包括操作者经验（χ=3.48，P<0.05）、导管留置时间（χ=7.478，P<0.05）、是否接受化疗（χ=2.43，P<0.05）、卡氏功能状态评分（χ=2.19，P<0.05）以及穿刺点更换敷贴的频率（χ=2.23）。Logistic回归分析显示，PICC导管留置时间（比值比[OR]=4.21，P<0.05）和操作者经验（OR=2.80，P<0.05）是影响PICC导管相关感染的独立因素。