Liu Qingxue, Wu Haiyan, Wang Jianjuan, Li Xi-Ming
Qingdao University, Qingdao Department of Anesthesiology, Linyi City People's Hospital Department of Anesthesiology, Shandong Lunan Ophthalmologic Hospital, Linyi, China.
Medicine (Baltimore). 2018 Mar;97(10):e0085. doi: 10.1097/MD.0000000000010085.
To explore the effects of Shenmai (SM) injection on the values of cardiac output (CO), stroke volume (SV), and the ejection fraction (EF) in patients treated with off-pump coronary artery bypass graft (OPCABG).
Forty patients undergoing OPCABG were randomly divided into SM group (n = 20) and the 5% glucose (G) group (n = 20). The control liquids were injected from the beginning of the operation to the start of coronary artery bypass graft (CABG). The values of CO, SV, and EF before induction (t1), at the beginning of operation (t2), 30 minutes after the start of operation (t3), at the beginning of coronary artery bypass graft (t4), at the end of coronary artery bypass graft (CABG) (t5), and at the end of operation (t6) were recorded.
The values of CO, SV, and EF in the patients of SM group at t3 to t6 were found to be significantly higher than those at t1 (P < .05). The values of CO, SV, and EF in the patients of G group were found to be increased at t5 and t6 (P < .05). At t3 and t4, the values of CO, SV, and EF in SM group were significantly higher than those in the G group (P < .05).
In patients with OPCABG, the infusion of SM injection can effectively increase the values of CO, SV, and EF and increase the safety of anesthesia management.
探讨参麦注射液对非体外循环冠状动脉搭桥术（OPCABG）患者心输出量（CO）、每搏输出量（SV）及射血分数（EF）的影响。
40例行OPCABG的患者随机分为参麦组（n = 20）和5%葡萄糖组（G组，n = 20）。从手术开始至冠状动脉搭桥（CABG）开始时输注对照液体。记录诱导前（t1）、手术开始时（t2）、手术开始后30分钟（t3）、冠状动脉搭桥开始时（t4）、冠状动脉搭桥结束时（t5）及手术结束时（t6）的CO、SV及EF值。
参麦组患者t3至t6时的CO、SV及EF值显著高于t1时（P < 0.05）。G组患者t5和t6时的CO、SV及EF值升高（P < 0.05）。t3和t4时，参麦组的CO、SV及EF值显著高于G组（P < 0.05）。
在OPCABG患者中，输注参麦注射液可有效提高CO、SV及EF值，并提高麻醉管理的安全性。
