Bao Changqian, Wei Juyin, Zhao Xin, Lin Lili, Chen Donghe, Liu Kanfeng, Qian Wenbin, Anas Jhurry Muhummad, Zhao Kui
Lymphoma center, the First Affiliated Hospital PET center, the First Affiliated Hospital, Medical School of Zhejiang University Program in Clinical Medicine, School of Medicine, Zhejiang University, Zhejiang, China.
Medicine (Baltimore). 2018 Mar;97(10):e9877. doi: 10.1097/MD.0000000000009877.
Primary hepatic mucosa-associated lymphoid tissue (MALT) lymphoma is extremely rare and we herein report a case of a patient suffering from primary hepatic MALT lymphoma with concomitant hepatitis B virus infection.
Double masses were found in a 59-year-old Chinese female patient. We reported the laboratory results, computed tomography (CT) and fluorine-18-fluorodeoxyglucose (F-FDG) positron emission tomography (PET)/CT images among other findings. As far as we know, only 9 cases have been reported till now using F-FDG PET/CT imaging. Our patient's lesions were found to conform to standard uptake values of FDG.
It indicates that hepatic MALT lymphoma can be studied with F-FDG PET/CT like other F-FDG-avid lymphomas. It was also noted that delayed-time-point FDG PET imaging may further improve the detection of the MALT lymphoma in liver. Although the patient in this case refused further treatment, potential management options, including rituximab, which is also discussed in this review.
原发性肝黏膜相关淋巴组织(MALT)淋巴瘤极为罕见,我们在此报告一例患有原发性肝MALT淋巴瘤并伴有乙型肝炎病毒感染的患者。
在一名59岁中国女性患者中发现了双肿块。我们报告了实验室检查结果、计算机断层扫描(CT)以及氟-18-氟脱氧葡萄糖(F-FDG)正电子发射断层扫描(PET)/CT图像等检查结果。据我们所知,截至目前使用F-FDG PET/CT成像报道的病例仅有9例。我们患者的病变被发现符合FDG的标准摄取值。
这表明肝MALT淋巴瘤可以像其他F-FDG摄取阳性淋巴瘤一样通过F-FDG PET/CT进行研究。还注意到延迟时间点的FDG PET成像可能会进一步提高肝脏中MALT淋巴瘤的检出率。尽管该病例患者拒绝进一步治疗,但本综述中也讨论了包括利妥昔单抗在内的潜在治疗方案。