Jiang Dapeng, Chen Zhoutong, Lin Houwei, Xu Maosheng, Geng Hongquan
Department of Urology, Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Urol Int. 2018;100(3):322-326. doi: 10.1159/000487196. Epub 2018 Mar 8.
This study was performed to analyze the predictive factors of a contralateral operation after initial pyeloplasty in patients with antenatally detected bilateral ureteropelvic junction obstruction.
Patients with prenatally diagnosed bilateral ureteropelvic junction obstruction who underwent initial pyeloplasty (aged <12 months at initial pyeloplasty) were offered to participate in the study. Patients were recruited from January 2012 to December 2015. The anteroposterior renal pelvic diameter, parenchymal thickness, and calyceal dilatation were evaluated. Predictive factors of contralateral pyeloplasty after initial unilateral pyeloplasty were also examined.
In total, 82 patients were included in the study (mean age, 2.8 months). Among all patients who underwent initial pyeloplasty, additional contralateral pyeloplasty was required in 11 patients (13.4%). The outcome of contralateral hydronephrosis was assessed as resolution, persistence, or surgery. The median anteroposterior renal pelvic diameter and calyceal dilatation were significantly different among the groups (p < 0.001). Calyceal dilatation of ≥10 mm and a calyceal dilatation/parenchymal thickness ratio of ≥5 strongly suggested the likelihood of a contralateral operation.
In most patients with bilateral ureteropelvic junction obstruction, improvement or resolution of contralateral hydronephrosis following initial unilateral pyeloplasty can be expected. Patients with contralateral calyceal dilatation >10 mm and the calyceal dilatation/parenchymal thickness ratio >5 are at higher risk of surgery.
本研究旨在分析产前诊断为双侧输尿管肾盂连接部梗阻的患者在初次肾盂成形术后对侧手术的预测因素。
邀请产前诊断为双侧输尿管肾盂连接部梗阻且接受初次肾盂成形术(初次肾盂成形术时年龄<12个月)的患者参与本研究。患者于2012年1月至2015年12月入组。评估肾盂前后径、实质厚度和肾盏扩张情况。还检查了初次单侧肾盂成形术后对侧肾盂成形术的预测因素。
本研究共纳入82例患者(平均年龄2.8个月)。在所有接受初次肾盂成形术的患者中,11例(13.4%)需要进行额外的对侧肾盂成形术。评估对侧肾积水的结果为缓解、持续或手术。各组间肾盂前后径中位数和肾盏扩张情况有显著差异(p<0.001)。肾盏扩张≥10 mm且肾盏扩张/实质厚度比≥5强烈提示对侧手术的可能性。
在大多数双侧输尿管肾盂连接部梗阻的患者中,初次单侧肾盂成形术后对侧肾积水有望改善或缓解。对侧肾盏扩张>10 mm且肾盏扩张/实质厚度比>5的患者手术风险较高。