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家鸽基因组组装与注释的改进( )。 (括号内原文缺失具体内容)

Improved Genome Assembly and Annotation for the Rock Pigeon ().

作者信息

Holt Carson, Campbell Michael, Keays David A, Edelman Nathaniel, Kapusta Aurélie, Maclary Emily, T Domyan Eric, Suh Alexander, Warren Wesley C, Yandell Mark, Gilbert M Thomas P, Shapiro Michael D

机构信息

Department of Human Genetics, University of Utah, Salt Lake City, UT, USA.

USTAR Center for Genetic Discovery, University of Utah, Salt Lake City, UT, USA.

出版信息

G3 (Bethesda). 2018 May 4;8(5):1391-1398. doi: 10.1534/g3.117.300443.

Abstract

The domestic rock pigeon () is among the most widely distributed and phenotypically diverse avian species. is broadly studied in ecology, genetics, physiology, behavior, and evolutionary biology, and has recently emerged as a model for understanding the molecular basis of anatomical diversity, the magnetic sense, and other key aspects of avian biology. Here we report an update to the genome reference assembly and gene annotation dataset. Greatly increased scaffold lengths in the updated reference assembly, along with an updated annotation set, provide improved tools for evolutionary and functional genetic studies of the pigeon, and for comparative avian genomics in general.

摘要

家鸽是分布最广、表型最多样化的鸟类物种之一。它在生态学、遗传学、生理学、行为学和进化生物学等领域得到了广泛研究,最近还成为理解解剖学多样性的分子基础、磁感以及鸟类生物学其他关键方面的模型。在此,我们报告家鸽基因组参考组装和基因注释数据集的更新情况。更新后的参考组装中支架长度大幅增加,同时注释集也得到更新,这为鸽子的进化和功能遗传学研究以及一般的鸟类比较基因组学提供了更好的工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbd/5940132/83e8f3695fa0/1391f1.jpg

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