Majc Dejan, Tepes Bojan
General Hospital Murska Sobota, Murska Sobota, Slovenia.
AM DC Rogaška, Rogaška Slatina, Slovenija.
Radiol Oncol. 2017 Dec 7;52(1):75-82. doi: 10.1515/raon-2017-0056. eCollection 2018 Mar.
In the study, we aimed to determine whether regular outpatient controls in patients with alcoholic liver cirrhosis have an impact on their survival and hospitalisation rates.
We included patients with liver cirrhosis and regular outpatient controls as a prospective study group and patients with liver cirrhosis who were admitted to hospital only in cases of complications as a retrospective control group. The study was conducted between 2006 and 2011.
We included 98 patients in the study group and 101 patients in the control group. There were more outpatient controls in the study group than in the control group (5.54 examinations vs. 2.27 examinations, p = 0.000). Patients in the study group had 25 fewer hospitalisations (10.2%; p = 0.612). The median survival rate was 4.6 years in the study group and 2.9 years in the control group (p = 0.021). Patients with Child A classification had an average survival of one year longer in the study group (p = 0.035). No significant difference was found for Child B patients. Patients with Child C classification had longer survival by 1.6 years in the study group (p = 0.006). Alcohol consumption was lower in the study group than in the control group (p = 0.018).
We confirmed that patients with regular outpatient controls had lower alcohol consumption, a lower hospitalisation rate and significantly prolonged survival time. We confirmed the necessity for the establishment of regular outpatient controls in patients with alcoholic liver cirrhosis.
在本研究中,我们旨在确定酒精性肝硬化患者的定期门诊检查是否会对其生存率和住院率产生影响。
我们将肝硬化且有定期门诊检查的患者纳入前瞻性研究组,将仅在出现并发症时才入院的肝硬化患者纳入回顾性对照组。该研究于2006年至2011年进行。
我们在研究组纳入了98例患者,在对照组纳入了101例患者。研究组的门诊检查次数多于对照组(5.54次检查对2.27次检查,p = 0.000)。研究组患者的住院次数少25次(10.2%;p = 0.612)。研究组的中位生存率为4.6年,对照组为2.9年(p = 0.021)。Child A分级的患者在研究组的平均生存期长一年(p = 0.035)。Child B级患者未发现显著差异。Child C分级的患者在研究组的生存期长1.6年(p = 0.006)。研究组的酒精摄入量低于对照组(p = 0.018)。
我们证实,有定期门诊检查患者的酒精摄入量较低、住院率较低且生存时间显著延长。我们证实了为酒精性肝硬化患者建立定期门诊检查的必要性。