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低峰值跳跃能力与社区居住的老年人群中运动障碍综合征的风险增加相关:韩国城乡老年人(KURE)研究。

Low peak jump power is associated with elevated odds of dysmobility syndrome in community-dwelling elderly individuals: the Korean Urban Rural Elderly (KURE) study.

机构信息

Department of Internal Medicine, Severance Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul, 120-752, Korea.

Graduate School, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Osteoporos Int. 2018 Jun;29(6):1427-1436. doi: 10.1007/s00198-018-4466-0. Epub 2018 Mar 8.

Abstract

UNLABELLED

In a community-dwelling elderly cohort (Korean Urban Rural Elderly), low peak jump power was associated with elevated odds of dysmobility syndrome and its components, independent of age and comorbidities. Jump power measurement improved discrimination of individuals with dysmobility syndrome when added to conventional risk factors.

INTRODUCTION

Dysmobility syndrome was proposed to encompass the risks affecting musculoskeletal outcomes. Jump power measurement is a safe, reproducible high-intensity test for physical function in elderly. However, the relationship between jump power and dysmobility syndrome remains unknown.

METHODS

A total of 1369 subjects (mean 71.6 years; women, 66%) were analyzed from a community-based cohort. Dysmobility syndrome was defined as the presence of ≥ 3 factors among falls in the preceding year, low lean mass, high fat mass, osteoporosis, low grip strength, and low timed get-up-and-go (TUG) performance. Subjects were grouped into tertiles of jump power relative to weight based on sex-stratified cutoffs (32.4 and 27.6 W/kg in men; 23.9 and 19.9 W/kg in women) or into the failed-to-jump group.

RESULTS

The prevalence of dysmobility syndrome was 20% overall, increasing from the highest (T1) to lowest (T3) jump power tertile (1, 11, 15% in men; 11, 16, 39% in women) and the failed-to-jump group (39% in men; 48% in women). Low jump power or failed-to-jump was associated with elevated odds of dysmobility syndrome (T3 vs. T1, adjusted odds ratio [aOR] 4.35, p < 0.001; failed-to-jump vs. T1, aOR 7.60, p < 0.001) and its components including falls, low lean mass, high fat mass, and poor TUG performance but not osteoporosis after adjustment for covariates. Jump power modestly discriminated dysmobility syndrome (area under the curve [AUC], 0.71, p < 0.001), which improved discriminatory performance when added to conventional risk factors (AUC, from 0.75 to 0.79, p < 0.001).

CONCLUSIONS

Low peak jump power was associated with elevated odds of dysmobility syndrome and its components, independent of age and comorbidities.

摘要

目的

在社区居住的老年队列(韩国城乡老年人)中,低峰值跳跃力与移动障碍综合征及其组成部分的几率升高相关,独立于年龄和合并症。跳跃力测量在添加常规危险因素后提高了对移动障碍综合征个体的区分能力。

背景

移动障碍综合征被提出包含影响肌肉骨骼结果的风险。跳跃力测量是一种安全、可重复的用于评估老年人身体功能的高强度测试。然而,跳跃力与移动障碍综合征之间的关系尚不清楚。

方法

对基于社区的队列中的 1369 名受试者(平均年龄 71.6 岁;女性占 66%)进行了分析。移动障碍综合征的定义为在过去一年中跌倒、低瘦体重、高脂肪量、骨质疏松症、握力低和计时起立行走(TUG)表现差的≥3 个因素。根据性别分层的截止值(男性 32.4 和 27.6 W/kg;女性 23.9 和 19.9 W/kg),将受试者按跳跃力相对于体重的三分位数分组,或者分为未跳跃组。

结果

移动障碍综合征的总体患病率为 20%,从最高(T1)到最低(T3)跳跃力三分位数(男性为 1、11、15%;女性为 11、16、39%)和未跳跃组(男性为 39%;女性为 48%)呈递增趋势。低跳跃力或未跳跃与移动障碍综合征的几率升高相关(T3 与 T1,调整后的优势比 [aOR] 4.35,p<0.001;未跳跃与 T1,aOR 7.60,p<0.001)以及跌倒、低瘦体重、高脂肪量和 TUG 表现差等组成部分,但在调整协变量后与骨质疏松症无关。跳跃力适度区分移动障碍综合征(曲线下面积 [AUC],0.71,p<0.001),当添加到常规危险因素时,可提高区分性能(AUC,从 0.75 增加到 0.79,p<0.001)。

结论

峰值跳跃力较低与移动障碍综合征及其组成部分的几率升高相关,独立于年龄和合并症。

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