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A-56268(TE-031)及其他四种抗菌剂对沙眼衣原体的体外活性

In vitro activity of A-56268 (TE-031) and four other antimicrobial agents against Chlamydia trachomatis.

作者信息

Segreti J, Kessler H A, Kapell K S, Trenholme G M

出版信息

Antimicrob Agents Chemother. 1987 Jan;31(1):100-1. doi: 10.1128/AAC.31.1.100.

Abstract

The in vitro activity of A-56268 (TE-031), a new macrolide antibiotic, against 11 strains of Chlamydia trachomatis was determined and compared with that of four other antibiotics. A-56268 was the most active drug tested. Doxycycline, trimethoprim-sulfamethoxazole, and erythromycin had good activity but were less active in vitro than A-56268.

摘要

新型大环内酯类抗生素A-56268(TE-031)对11株沙眼衣原体的体外活性进行了测定,并与其他四种抗生素进行了比较。A-56268是所测试药物中活性最强的。强力霉素、甲氧苄啶-磺胺甲恶唑和红霉素活性良好,但体外活性低于A-56268。

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