Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences·Key Laboratory of Animal Diseases, Diagnostics, and Immunology, Ministry of Agriculture·Key Laboratory of Food Quality and Safety of Jiangsu Province-State Key Laboratory Breeding Base, Nanjing, China.
Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infections Diseases and Zoonoses, Yangzhou, China.
Transbound Emerg Dis. 2018 Oct;65(5):1364-1366. doi: 10.1111/tbed.12855. Epub 2018 Mar 8.
A large outbreak of swine abortion, which began in January 2017, is ongoing in Jiangsu and Anhui provinces, China. We identified a new porcine circovirus-like agent, designated P4, in the aborted foetuses from several of these cases of swine reproductive failure. PCR and qRT-PCR analyses confirmed that other common abortogenic agents were not present in these animals. P4 contains a 710-nucleotide circular viral genome, and all strains examined in this study were closely related to the dominant genotype of porcine circovirus type 2. Further studies, such as in vivo analyses, are needed to confirm P4 as the aetiological agent.
2017 年 1 月以来，中国江苏和安徽发生了一起大规模猪流产疫情。我们从这些猪繁殖障碍病例的流产胎儿中鉴定到一种新的猪圆环病毒样病毒，暂命名为 P4。PCR 和 qRT-PCR 分析确认这些动物中不存在其他常见的致流产病原体。P4 含有一个 710 个核苷酸的环状病毒基因组，本研究中检测到的所有毒株均与猪圆环病毒 2 型的优势基因型密切相关。需要进一步的研究，如体内分析，以确认 P4 是该病的病原体。
