Bassilios Habre Samer, Depew James Bradford, Wallace Robert D, Konofaos Petros
Department of Plastic Surgery, University of Tennessee Health Sciences Center, Memphis, TN.
J Craniofac Surg. 2018 Jun;29(4):1023-1025. doi: 10.1097/SCS.0000000000004439.
Neuroma pain can be severe, persistent, and treatment-resistant. Forehead and scalp anesthesia is troublesome for patients. Following an iatrogenic ablative injury to the right supraorbital nerve, with subsequent painful neuroma formation, a human cadaveric nerve allograft (AxoGen, Alachua, FL) was used to restore sensation of the right forehead and treat pain. At 1-year follow-up, the patient was pain-free, and protective sensation to the right forehead was recovered with comparable static and dynamic 2-point discrimination between the injured (20 mm, 12 mm respectively) and the normal side (15 mm, 10 mm respectively). This is the first reported case of using a cadaver nerve allograft for successful direct neurotization of the skin and restoration of sensation in the upper part of the face, and for treating painful neuromas. Moreover, a brief review of the available techniques for treating neuromas of the supraorbital and supratrochlear nerves is provided.
神经瘤疼痛可能严重、持续且难以治疗。前额和头皮麻醉对患者来说很麻烦。在右侧眶上神经发生医源性消融损伤并随后形成疼痛性神经瘤后,使用人尸体神经同种异体移植物(AxoGen,阿拉楚阿,佛罗里达州)来恢复右侧前额的感觉并治疗疼痛。在1年的随访中,患者无痛,右侧前额的保护性感觉得以恢复,受伤侧(分别为20毫米、12毫米)与正常侧(分别为15毫米、10毫米)之间的静态和动态两点辨别力相当。这是首例使用尸体神经同种异体移植物成功实现面部上部皮肤直接神经化、恢复感觉并治疗疼痛性神经瘤的报道病例。此外,还对治疗眶上神经和滑车上神经神经瘤的现有技术进行了简要综述。