• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

靶向乳头乳晕复合体再支配：基于植入物的乳房重建中的技术考量与手术效率

Targeted Nipple Areola Complex Reinnervation: Technical Considerations and Surgical Efficiency in Implant-based Breast Reconstruction.

作者信息

Gfrerer Lisa, Sager Jessica Erdmann, Ford Olivia Abbate, Carty Matthew J, Verdial Francys C, Gadd Michele A, Specht Michelle C, Winograd Jonathan M, Valerio Ian L

机构信息

Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.

Division of Plastic and Reconstructive Surgery, Brigham and Womens Hospital, Harvard Medical School, Boston, Mass.

出版信息

Plast Reconstr Surg Glob Open. 2022 Jul 25;10(7):e4420. doi: 10.1097/GOX.0000000000004420. eCollection 2022 Jul.

DOI:10.1097/GOX.0000000000004420
PMID:35923997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9325332/
Abstract

BACKGROUND

Despite promising pilot study results, adoption of neurotization of immediate implant-based reconstructions has not occurred.

METHODS

For surgeons interested in adopting breast reinnervation techniques, we present ways to overcome initial barriers by decreasing operative time and maximizing chances of sensory recovery.

RESULTS

We discuss the combined experience at two academic teaching hospitals, where neurotization of both immediate tissue expander cases and direct-to-implant reconstructions are performed through varying mastectomy incisions.

CONCLUSION

Initial barriers can be overcome by shortening operative time and providing an individualized reinnervation approach that aims to increase the chance of meaningful sensation.

摘要

背景

尽管初步研究结果令人鼓舞，但基于即刻植入物重建的神经化技术尚未得到广泛应用。

方法

对于有兴趣采用乳房再神经化技术的外科医生，我们介绍了通过减少手术时间和最大化感觉恢复机会来克服初始障碍的方法。

结果

我们讨论了两家学术教学医院的综合经验，在那里，通过不同的乳房切除术切口对即刻组织扩张器病例和直接植入式重建进行神经化。

结论

可以通过缩短手术时间和提供个性化的再神经化方法来克服初始障碍，该方法旨在增加有意义感觉的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29f8/9325332/2ea43ff93521/gox-10-e4420-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29f8/9325332/36dc9cad3db2/gox-10-e4420-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29f8/9325332/2ea43ff93521/gox-10-e4420-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29f8/9325332/36dc9cad3db2/gox-10-e4420-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29f8/9325332/2ea43ff93521/gox-10-e4420-g002.jpg

相似文献

1
Targeted Nipple Areola Complex Reinnervation: Technical Considerations and Surgical Efficiency in Implant-based Breast Reconstruction.靶向乳头乳晕复合体再支配：基于植入物的乳房重建中的技术考量与手术效率
Plast Reconstr Surg Glob Open. 2022 Jul 25;10(7):e4420. doi: 10.1097/GOX.0000000000004420. eCollection 2022 Jul.
2
Comparison of Outcomes with Tissue Expander, Immediate Implant, and Autologous Breast Reconstruction in Greater Than 1000 Nipple-Sparing Mastectomies.1000余例保留乳头的乳房切除术中组织扩张器、即刻植入物和自体乳房重建的结局比较
Plast Reconstr Surg. 2017 Jun;139(6):1300-1310. doi: 10.1097/PRS.0000000000003340.
3
Favorable Outcome with Close Margins in Patients Undergoing Nipple/Skin Sparing Mastectomy with Immediate Breast Reconstruction: 5-year Follow-up.保乳乳头/皮肤切除术即刻乳房重建术患者边缘切缘接近时的良好转归：5 年随访。
Balkan Med J. 2018 Jan 20;35(1):84-92. doi: 10.4274/balkanmedj.2017.0029. Epub 2017 Sep 29.
4
Pure hemi-periareolar incision versus conventional lateral radial incision mastectomy and direct-to-implant breast reconstructions: comparison of indocyanine green angiographic perfusion and necrosis of the nipple.单纯乳晕半周切口与传统外侧放射状切口乳房切除术及即刻乳房重建术：吲哚菁绿血管造影灌注与乳头坏死的比较
Gland Surg. 2020 Oct;9(5):1193-1204. doi: 10.21037/gs-20-506.
5
Targeted Nipple Areola Complex Reinnervation in Gender-affirming Double Incision Mastectomy with Free Nipple Grafting.在性别确认双切口乳房切除术并游离乳头移植术中进行靶向乳头乳晕复合体再支配。
Plast Reconstr Surg Glob Open. 2022 Apr 14;10(4):e4251. doi: 10.1097/GOX.0000000000004251. eCollection 2022 Apr.
6
Bilateral prophylactic mastectomy in BRCA mutation carriers: what surgeons need to know.BRCA 突变携带者的双侧预防性乳房切除术：外科医生需要了解的内容。
Ann Ital Chir. 2019;90:1-2.
7
Comparative Study of Nipple-Areola Complex Position and Patient Satisfaction After Unilateral Mastectomy and Immediate Expander-Implant Reconstruction Nipple-Sparing Mastectomy Versus Skin-Sparing Mastectomy.单侧乳房切除术和即刻扩张器-植入物重建乳头保留乳房切除术与皮肤保留乳房切除术的乳头乳晕复合体位置比较研究及患者满意度。
Aesthetic Plast Surg. 2019 Apr;43(2):313-327. doi: 10.1007/s00266-018-1217-8. Epub 2019 Feb 11.
8
Neurotization of the Nipple-Areola Complex during Implant-Based Reconstruction: Evaluation of Early Sensation Recovery.神经化乳头乳晕复合体在基于植入物的重建过程中的应用：早期感觉恢复的评估。
Plast Reconstr Surg. 2020 Aug;146(2):250-254. doi: 10.1097/PRS.0000000000006976.
9
Breast reconstruction following subcutaneous mastectomy for cancer: a critical appraisal of the nipple-areola complex.癌症皮下乳房切除术后的乳房重建：乳头乳晕复合体的批判性评估
Plast Reconstr Surg. 2006 Apr;117(4):1083-90. doi: 10.1097/01.prs.0000202103.78284.97.
10
Immediate targeted nipple-areolar complex re-innervation: Improving outcomes in immediate autologous breast reconstruction.即刻靶向乳晕复合体再神经化：改善即刻自体乳房重建的结局。
J Plast Reconstr Aesthet Surg. 2021 Jul;74(7):1503-1507. doi: 10.1016/j.bjps.2020.11.021. Epub 2020 Dec 3.

引用本文的文献

1
Nipple-Areolar Complex Neurotization Following Nipple-sparing Mastectomy and Breast Reconstruction for Solitary Breast Neurofibroma.保留乳头的乳房切除术后乳头乳晕复合体神经化及针对孤立性乳腺神经纤维瘤的乳房重建
Plast Reconstr Surg Glob Open. 2025 May 22;13(5):e6814. doi: 10.1097/GOX.0000000000006814. eCollection 2025 May.
2
Effect of Intercostal Nerve Coaptation on Postoperative Pain in Implant-Based Breast Reconstruction: A Double-Blind, Randomized Controlled Pilot Study.肋间神经吻合术对乳房假体植入乳房重建术后疼痛的影响：一项双盲、随机对照试验性研究
J Breast Cancer. 2025 Apr;28(2):108-118. doi: 10.4048/jbc.2024.0212. Epub 2025 Mar 4.
3

本文引用的文献

1
Dermatosensory Peripheral Nerve Interfaces: Prevention of Pain Recurrence Following Sensory Neurectomy.皮感觉外周神经界面：感觉神经切断术后疼痛复发的预防。
Hand Clin. 2021 Aug;37(3):383-389. doi: 10.1016/j.hcl.2021.05.005.
2
Long Acellular Nerve Allografts Cap Transected Nerve to Arrest Axon Regeneration and Alter Upstream Gene Expression in a Rat Neuroma Model.长去细胞神经同种异体移植物可阻断切断神经以阻止轴突再生，并改变大鼠神经瘤模型中的上游基因表达。
Plast Reconstr Surg. 2021 Jul 1;148(1):32e-41e. doi: 10.1097/PRS.0000000000008051.
3
Targeted sensory reinnervation by direct neurotization of skin: An experimental study in rats.
Commentary: Examination of Sensory Recovery of Breasts Reconstructed With Silicone Breast Implants After Nipple-Sparing Mastectomy.
评论：保乳乳头切除术后使用硅胶乳房植入物重建乳房的感觉恢复检查
Plast Surg (Oakv). 2025 Feb;33(1):14-15. doi: 10.1177/22925503231203224. Epub 2023 Oct 4.
4
Reinnervation of Free Nipple Grafts Associated With Improved Erection Function.游离乳头移植再神经支配与勃起功能改善相关
Plast Reconstr Surg Glob Open. 2025 Jan 13;13(1):e6418. doi: 10.1097/GOX.0000000000006418. eCollection 2025 Jan.
5
Diagnosis and Management of Neuropathic Breast Pain.神经性乳腺疼痛的诊断与管理
Plast Reconstr Surg Glob Open. 2024 Dec 23;12(12):e6266. doi: 10.1097/GOX.0000000000006266. eCollection 2024 Dec.
6
Careful Where You Cut: Strategies for Successful Nerve-preserving Mastectomy.手术切割需谨慎：保留神经的成功乳房切除术策略
Plast Reconstr Surg Glob Open. 2024 May 15;12(5):e5817. doi: 10.1097/GOX.0000000000005817. eCollection 2024 May.
7
Sensate immediate breast reconstruction.感觉即刻乳房重建。
Gland Surg. 2024 Apr 29;13(4):552-560. doi: 10.21037/gs-23-416. Epub 2024 Apr 12.
8
Counselling Framework for Germline and Carriers Considering Risk-Reducing Mastectomy.胚系和携带者考虑降低风险的乳房切除术的咨询框架。
Curr Oncol. 2024 Jan 9;31(1):350-365. doi: 10.3390/curroncol31010023.
9
Prospective Sensory Outcomes for Targeted Nipple-areola Complex Reinnervation in Gender-affirming Double Incision Mastectomy With Free Nipple Grafting.在采用游离乳头移植的性别肯定性双切口乳房切除术中，靶向乳头乳晕复合体再支配的前瞻性感觉结果。
Ann Surg. 2025 Jul 1;282(1):163-171. doi: 10.1097/SLA.0000000000006192. Epub 2024 Jan 12.
10
Targeted Nipple Reinnervation in Gender-affirming Mastectomy Using Autologous Nerve Graft.在性别肯定性乳房切除术中使用自体神经移植进行靶向乳头再支配。
Plast Reconstr Surg Glob Open. 2023 Sep 15;11(9):e5203. doi: 10.1097/GOX.0000000000005203. eCollection 2023 Sep.
靶向感觉神经再支配通过皮肤的直接神经化：大鼠的实验研究。
J Plast Reconstr Aesthet Surg. 2021 Sep;74(9):2379-2386. doi: 10.1016/j.bjps.2020.12.101. Epub 2021 Jan 10.
4
Targeted Muscle Reinnervation at the Time of Major Limb Amputation in Traumatic Amputees: Early Experience of an Effective Treatment Strategy to Improve Pain.创伤性截肢患者大肢体截肢时的靶向肌肉再支配：一种改善疼痛的有效治疗策略的早期经验
JB JS Open Access. 2020 May 6;5(2):e0067. doi: 10.2106/JBJS.OA.19.00067. eCollection 2020 Apr-Jun.
5
Neurotization of the Nipple-Areola Complex during Implant-Based Reconstruction: Evaluation of Early Sensation Recovery.神经化乳头乳晕复合体在基于植入物的重建过程中的应用：早期感觉恢复的评估。
Plast Reconstr Surg. 2020 Aug;146(2):250-254. doi: 10.1097/PRS.0000000000006976.
6
Treatment of Neuroma-induced Chronic Pain and Management of Nerve Defects with Processed Nerve Allografts.使用处理过的同种异体神经移植物治疗神经瘤引起的慢性疼痛及管理神经缺损
Plast Reconstr Surg Glob Open. 2019 Dec 19;7(12):e2467. doi: 10.1097/GOX.0000000000002467. eCollection 2019 Dec.
7
Targeted Muscle Reinnervation following Breast Surgery: A Novel Technique.乳房手术后的靶向肌肉再支配：一种新技术。
Plast Reconstr Surg Glob Open. 2020 Apr 24;8(4):e2782. doi: 10.1097/GOX.0000000000002782. eCollection 2020 Apr.
8
The role of vascularization in nerve regeneration of nerve graft.血管化在神经移植神经再生中的作用。
Neural Regen Res. 2020 Sep;15(9):1573-1579. doi: 10.4103/1673-5374.276327.
9
A novel approach to sensory re-innervation to the nipple areolar complex after mastectomy with implant-based reconstruction: Anatomic and technical considerations.一种基于植入物重建的乳房切除术后乳头乳晕复合体感觉再支配的新方法：解剖学和技术考量
J Plast Reconstr Aesthet Surg. 2020 May;73(5):983-1007. doi: 10.1016/j.bjps.2020.01.013. Epub 2020 Jan 21.
10
Nerve Preservation and Allografting for Sensory Innervation Following Immediate Implant Breast Reconstruction.即刻植入式乳房重建术后感觉神经支配的神经保留与同种异体移植
Plast Reconstr Surg Glob Open. 2019 Jul 24;7(7):e2332. doi: 10.1097/GOX.0000000000002332. eCollection 2019 Jul.