Center for Infertility and Reproductive Surgery, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
Center for Infertility and Reproductive Surgery, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
J Minim Invasive Gynecol. 2018 Sep-Oct;25(6):980-985. doi: 10.1016/j.jmig.2018.03.001. Epub 2018 Mar 7.
To evaluate the opinions and attitudes of the general public regarding uterine transplantation (UTx) in the United States.
A cross-sectional study (Canadian Task Force classification II-2).
A Web-based survey.
A nationally representative sample of adult US residents by age and sex.
A Web-based questionnaire administered in November 2016.
Respondents who supported UTx were compared with those who were opposed using log binomial regression to calculate relative risk ratios and 95% confidence intervals. Of the 1444 respondents recruited, 1337 (93%) completed the survey. Ninety respondents (6%) disagreed with the use of in vitro fertilization for any indication and were excluded. Of the remaining 1247 respondents, 977 (78%) supported and 48 (4%) opposed allowing women to undergo UTx. Respondents with higher yearly incomes and education level were more likely to agree that "taking the uterus from one person and putting it into another person is ethical." Respondents who answered that UTx is safe for the donor, recipient, and baby were more likely to believe that UTx is an acceptable, ethical alternative to a gestational carrier. Forty-five percent of respondents believed that UTx should be covered by insurance, whereas 24% did not.
The majority of respondents in a sample of US residents support UTx, find it ethical, and believe that it is an acceptable alternative to a gestational carrier although support varies. These findings suggest that the US public is in favor of uterine transplantation as a treatment for uterine factor infertility.
评估美国公众对子宫移植（UTx）的意见和态度。
横断面研究（加拿大任务组分类 II-2）。
基于网络的调查。
按年龄和性别在全美范围内抽取的成年美国居民的代表性样本。
2016 年 11 月进行的基于网络的问卷调查。
使用对数二项式回归计算相对风险比和 95%置信区间，比较支持 UTx 的受访者与反对 UTx 的受访者。在招募的 1444 名受访者中，有 1337 名（93%）完成了调查。90 名（6%）不同意将体外受精用于任何指征的受访者被排除在外。在其余的 1247 名受访者中，977 名（78%）支持，48 名（4%）反对允许女性接受 UTx。年收入和教育水平较高的受访者更有可能认为“将子宫从一个人身上取出并植入另一个人身上是合乎道德的”。回答 UTx 对供体、受体和婴儿安全的受访者更有可能认为 UTx 是代孕的一种可接受的、合乎道德的替代方法。45%的受访者认为 UTx 应该由保险覆盖，而 24%的受访者则不认为应该由保险覆盖。
在一项美国居民样本中，大多数受访者支持 UTx，认为其合乎道德，并且认为这是代孕的一种可接受的替代方法，尽管支持程度有所不同。这些发现表明，美国公众支持子宫移植作为子宫因素不孕的治疗方法。
