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严重钙化性主动脉瓣狭窄病例的顺行性经皮经间隔瓣膜成形术

Anterograde percutaneous transseptal valvuloplasty in a case of severe calcific aortic stenosis.

作者信息

Grollier G, Commeau P, Agostini D, Durand C, Foucault J P, Potier J C

出版信息

Eur Heart J. 1987 Feb;8(2):190-3. doi: 10.1093/oxfordjournals.eurheartj.a062248.

DOI:10.1093/oxfordjournals.eurheartj.a062248
PMID:2952504
Abstract

The retrograde catheterization and percutaneous dilatation of calcific stenotic aortic valves is not always possible in elderly patients. We report the case of a 76-year old woman admitted with severe aortic stenosis in whom it was impossible to reach the left ventricle retrogradely. This led us to attempt percutaneous aortic valvuloplasty using a transseptal anterograde approach. The Mullins transseptal sheath catheter was advanced into the left ventricle and a 7 F catheter containing a long guide wire (400 cm) passed through the sheath. The flexible end of the guide wire was advanced through the aortic valve anterogradely and an angled wireloop retriever used to catch the flexible end of the guide wire and to draw it out of the body through the left femoral artery. A 7 F balloon catheter was introduced percutaneously over the long guide wire and allowed dilatation of the interatrial septum and femoral vein. A 8 F Schneider-Grüntzig catheter (80 mm) length, 19 mm diameter when inflated) was inserted anterogradely through the aortic valve over the guide wire without difficulty and the balloon catheter was inflated to a pressure of 6 atmospheres with a 30 seconds inflation-deflation cycle. Before the procedure the mean aortic valvular gradient was 114 mmHg and the aortic valve area was 0.30 cm2. After the procedure the mean aortic gradient had fallen to 60 mm Hg and the valve area had risen to 0.90 cm2. These results are comparable to those expected using the more usual retrograde balloon dilatation of the aortic valve.

摘要

对于老年患者,逆行导管插入术及经皮扩张钙化性狭窄主动脉瓣并非总是可行。我们报告一例76岁女性患者,因严重主动脉瓣狭窄入院,无法逆行进入左心室。这促使我们尝试采用经房间隔顺行途径进行经皮主动脉瓣成形术。将穆林斯经房间隔鞘管导管推进至左心室,一根装有长导丝(400厘米)的7F导管穿过鞘管。导丝的柔性末端顺行穿过主动脉瓣,使用成角度的导丝圈套器捕捉导丝的柔性末端,并通过左股动脉将其引出体外。一根7F球囊导管经皮沿长导丝置入,对房间隔和股静脉进行扩张。一根8F施耐德-格鲁恩齐格导管(长度80毫米,充气时直径19毫米)沿导丝轻松顺行穿过主动脉瓣插入,球囊导管以6个大气压的压力充气,充气-放气周期为30秒。术前主动脉瓣平均压差为114毫米汞柱,主动脉瓣面积为0.30平方厘米。术后主动脉平均压差降至60毫米汞柱,瓣膜面积升至0.90平方厘米。这些结果与使用更常见的主动脉瓣逆行球囊扩张术预期的结果相当。

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