Vandormael M, Deligonul U, Gabliani G, Chaitman B, Kern M J
Cardiac Catheterization Laboratory, St. Louis University Medical Center, MO 63104.
Cathet Cardiovasc Diagn. 1988;14(1):49-52. doi: 10.1002/ccd.1810140112.
An 81-year-old man with severe calcific aortic stenosis and coronary artery disease who refused surgical therapy was treated with sequential percutaneous balloon aortic valvuloplasty (PBAV) and percutaneous transluminal angioplasty. Before percutaneous balloon valvuloplasty, the mean aortic gradient was 76 mmHg, and the aortic valve area was .45 cm2. The aortic valve was dilated using 15-mm and 18-mm balloons. The mean gradient decreased to 40 mmHG, and the aortic valve area increased to .62 cm2. Percutaneous transluminal coronary angioplasty (PTCA) was performed 2 weeks later, and an 85% proximal left circumflex stenosis was successfully dilated to 20%. No complications were noted during either procedure. At 6-month follow-up, the patient had returned to normal activities and was asymptomatic. Thus, combined therapy with PBAV and PTCA is technically feasible in selected elderly patients with calcific aortic stenosis and anatomically suitable coronary artery disease. This nonsurgical therapeutic approach may be useful in the treatment of selected patients who refuse or who are deferred from cardiac surgery.
一名患有严重钙化性主动脉瓣狭窄和冠状动脉疾病且拒绝手术治疗的81岁男性,接受了序贯经皮球囊主动脉瓣成形术(PBAV)和经皮腔内血管成形术治疗。在经皮球囊瓣膜成形术前,平均主动脉压差为76 mmHg,主动脉瓣面积为0.45 cm²。使用15 mm和18 mm的球囊扩张主动脉瓣。平均压差降至40 mmHg,主动脉瓣面积增至0.62 cm²。两周后进行了经皮腔内冠状动脉成形术(PTCA),左旋支近端85%的狭窄成功扩张至20%。两种手术过程中均未发现并发症。在6个月的随访中,患者已恢复正常活动且无症状。因此,对于选定的患有钙化性主动脉瓣狭窄且解剖结构适合的冠状动脉疾病的老年患者,PBAV和PTCA联合治疗在技术上是可行的。这种非手术治疗方法可能对拒绝或推迟心脏手术的选定患者的治疗有用。