Department of Orthopaedic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.
Department of Orthopaedics, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, People's Republic of China.
J Arthroplasty. 2018 Jul;33(7):2087-2091. doi: 10.1016/j.arth.2018.02.041. Epub 2018 Feb 17.
The aim of this study was to identify the incidence and risk factors for blood transfusion in patients undergoing simultaneous bilateral total hip arthroplasty (SBTHA) and simultaneous bilateral total knee arthroplasty (SBTKA).
We identified 414 SBTHA and 1147 SBTKA procedures, and separated the patients into those who did and did not require allogeneic blood transfusion. A multivariate logistic regression model was used to identify independent risk factors for transfusion.
The transfusion rate after SBTHA was 50.0%, and significant risk factors for transfusion were female gender (odds ratio [OR] = 2.612), lower body mass index (OR = 1.093), inflammatory arthritis (OR = 1.970), American Society of Anesthesiologists (ASA) class ≥3 (OR = 3.477), drain use (OR = 4.607), and increased intraoperative bleeding. We also found that higher preoperative hemoglobin (Hb) and tranexamic acid use decreased the risk of transfusion. The transfusion rate after SBTKA was 29.1%, and significant risk factors for transfusion were ASA class ≥3 (OR = 8.959), tourniquet use (OR = 2.129), drain use (OR = 4.970), and increased intraoperative bleeding. A higher preoperative Hb was the only protective factor for transfusion.
For SBTHA, the risk factors included female gender, lower body mass index, inflammatory arthritis, ASA class ≥3, drain use, and increased intraoperative bleeding, while for SBTKA, risk factors were ASA class ≥3, tourniquet use, drain use, and increased intraoperative bleeding. Increasing the preoperative Hb level may decrease transfusion risk. In addition, tranexamic acid was encouraged to use to decrease transfusion need in SBTHA.
本研究旨在确定同时行双侧全髋关节置换术(SBTHA)和同时行双侧全膝关节置换术(SBTKA)患者输血的发生率和相关危险因素。
我们共纳入了 414 例 SBTHA 和 1147 例 SBTKA 手术患者,并根据是否需要异体输血将患者分为两组。采用多变量逻辑回归模型确定输血的独立危险因素。
SBTHA 术后的输血率为 50.0%,输血的显著危险因素包括女性(比值比[OR] = 2.612)、较低的体重指数(OR = 1.093)、炎症性关节炎(OR = 1.970)、美国麻醉医师协会(ASA)分级≥3 级(OR = 3.477)、引流管使用(OR = 4.607)和术中出血量增加。我们还发现,较高的术前血红蛋白(Hb)和氨甲环酸的使用降低了输血的风险。SBTKA 术后的输血率为 29.1%,输血的显著危险因素包括 ASA 分级≥3 级(OR = 8.959)、止血带使用(OR = 2.129)、引流管使用(OR = 4.970)和术中出血量增加。较高的术前 Hb 是唯一的输血保护因素。
对于 SBTHA,危险因素包括女性、较低的体重指数、炎症性关节炎、ASA 分级≥3 级、引流管使用和术中出血量增加,而对于 SBTKA,危险因素包括 ASA 分级≥3 级、止血带使用、引流管使用和术中出血量增加。增加术前 Hb 水平可能会降低输血风险。此外,鼓励在 SBTHA 中使用氨甲环酸以减少输血需求。