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同期双侧全髋关节置换术联合当代血液管理与异体输血风险低相关。

Simultaneous Bilateral Total Hip Arthroplasty With Contemporary Blood Management is Associated With a Low Risk of Allogeneic Blood Transfusion.

机构信息

Department of Orthopedics, Hospital for Special Surgery, New York, NY.

Department of Biostatistics, Hospital for Special Surgery, New York, NY.

出版信息

J Arthroplasty. 2022 Mar;37(3):544-548. doi: 10.1016/j.arth.2021.11.039. Epub 2021 Dec 6.

DOI:10.1016/j.arth.2021.11.039
PMID:34883254
Abstract

BACKGROUND

There is a paucity of data on blood loss and the risk of allogeneic blood transfusion after simultaneous bilateral total hip arthroplasty (SBTHA) with contemporary blood management including neuraxial anesthesia, routine tranexamic acid use, and a restrictive transfusion protocol. As such, we sought to determine the in-hospital outcomes of SBTHA, specifically analyzing blood loss and the rate and risk factors for transfusion.

METHODS

We identified 191 patients who underwent SBTHA at a single institution from 2016 to 2019. No drains were utilized and no patients donated blood preoperatively. Mean age was 59 years with 96 females (50.3%). The surgical approach was posterior in 138 (72.3%) and direct anterior in 53 (27.7%) patients. We analyzed blood loss, the rate of allogeneic blood transfusions, and in-hospital thromboembolic complications. We analyzed risk factors for transfusion with a logistic regression analysis.

RESULTS

Twenty-two patients (11.5%) underwent allogeneic blood transfusion. All transfused patients were female. Univariate analysis revealed female gender as a transfusion risk factor since it had statistically significant higher proportion in the transfusion group than the nontransfusion group (100% vs 43.5%, respectively, P < .001). We did not identify any other singular significant risk factors for transfusion in a multivariable regression analysis. However, females with a preoperative Hb <12 had an elevated risk of transfusion at 37.5% (15/40 patients).

CONCLUSION

With contemporary perioperative blood management protocols, there is a relatively low (11.5%) risk of a blood transfusion after SBTHA. Females with a lower preoperative Hb (<12 g/dL) had the highest risk of transfusion at 37.5%.

摘要

背景

在同时进行双侧全髋关节置换术 (SBTHA) 并采用当代血液管理方法(包括脊麻、常规使用氨甲环酸和限制性输血方案)的情况下,关于失血量和异体输血风险的数据很少。因此,我们旨在确定 SBTHA 的住院期间结局,特别是分析失血量以及输血的发生率和危险因素。

方法

我们在一家医疗机构确定了 191 例在 2016 年至 2019 年期间接受 SBTHA 的患者。未使用引流管,也没有患者术前献血。平均年龄为 59 岁,女性 96 例(50.3%)。手术入路为后路 138 例(72.3%),直接前路 53 例(27.7%)。我们分析了失血量、异体输血率和住院期间血栓栓塞并发症。我们使用逻辑回归分析来分析输血的危险因素。

结果

22 例患者(11.5%)接受了异体输血。所有输血患者均为女性。单因素分析显示,女性是输血的危险因素,因为在输血组中女性的比例明显高于非输血组(分别为 100%和 43.5%,P <.001)。在多变量回归分析中,我们没有发现任何其他单一的输血显著危险因素。然而,术前 Hb <12 的女性输血风险升高,达 37.5%(40 例患者中有 15 例)。

结论

在采用当代围手术期血液管理方案的情况下,SBTHA 后输血的风险相对较低(11.5%)。术前 Hb 较低(<12 g/dL)的女性输血风险最高,达 37.5%。

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