Cruz-Gonzalez Ignacio, Fuertes-Barahona Monica, Moreno-Samos Jose C, Gonzalez-Ferreiro Rocio, Lam Yan Yin, Sanchez Pedro L
Cardiology Department, University Hospital of Salamanca, Biomedical Research Institute of Salamanca (IBSAL), CIBER-CV, Paseo San Vicente, Salamanca 37007, Spain.
Cardiology Department, University Hospital of Salamanca, Biomedical Research Institute of Salamanca (IBSAL), CIBER-CV, Paseo San Vicente, Salamanca 37007, Spain.
Interv Cardiol Clin. 2018 Apr;7(2):253-265. doi: 10.1016/j.iccl.2017.12.011.
Since the first percutaneous left atrial appendage occlusion (LAAO), many studies have shown the safety and efficacy of this technique to prevent embolic strokes in nonvavular atrial fibrillation. The design, characteristics, and clinical data of the most frequently used devices for LAAO are reviewed, including the Amplatzer cardiac plug and Amulet (Abbott Vascular), the Watchman (Boston Scientific), and the LARIAT device (SentreHEART). Similarly, newer closer devices, such as Ultraseal (Cardia), LAmbre (Lifetech), and Coherex WaveCrest (Johnson & Johnson), are also discussed. Finally, new technologies still in the stage of preclinical study or in the initial clinical experience are also reviewed.
自首次经皮左心耳封堵术（LAAO）以来，许多研究已证实该技术在预防非瓣膜性心房颤动患者发生栓塞性卒中方面的安全性和有效性。本文综述了LAAO最常用器械的设计、特点及临床数据，包括Amplatzer心脏封堵器和Amulet（雅培血管）、Watchman（波士顿科学）以及LARIAT器械（SentreHEART）。同样，也讨论了更新的封闭器械，如Ultraseal（Cardia）、LAmbre（微创医疗）和Coherex WaveCrest（强生）。最后，还综述了仍处于临床前研究阶段或初始临床应用阶段的新技术。
