Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.
Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA; Yale-New Haven Transplantation Center, New Haven, Connecticut, USA.
J Pain Symptom Manage. 2018 Jul;56(1):44-52. doi: 10.1016/j.jpainsymman.2018.03.001. Epub 2018 Mar 8.
The prevalence of psychiatric disorders and mental health service utilization among patients with end-stage liver disease awaiting transplant remains understudied.
This study assessed the prevalence of psychological disorders and symptoms with the use of a structured diagnostic interview and self-report measures, and examined patient-reported mental health service utilization and barriers to care.
Waitlisted liver transplant candidates (N = 120) completed assessments during routine clinic appointments at a single time point.
Participants endorsed moderate-to-severe levels of depression (19.2%), anxiety (26.7%), and Post Traumatic Stress Disorder (PTSD) (23.3%). Forty-three percent had received some form of mental health treatment in the recent past, and a range of barriers to accessing mental health services were endorsed. In a subset of 39 participants who received a structure diagnostic assessment, there was a high prevalence of current (51.3%) and past (82.1%) psychiatric disorders. Elevated scores on depression, anxiety, and PTSD measures were associated with significant decrements in health-related quality of life, but were not differentially associated with mental health service utilization.
There are a significant number of end-stage liver disease patients who could benefit from intervention who are not currently connected to treatment. Many patients do not see the need for accessing services, perhaps because of a lack of insight or knowledge about the benefits of mental health treatment. Future research should determine optimal treatment and service delivery methods for this vulnerable population.
在等待肝移植的终末期肝病患者中,精神障碍和精神卫生服务的利用情况仍然研究不足。
本研究使用结构化诊断访谈和自我报告措施评估心理障碍和症状的患病率,并调查患者报告的精神卫生服务利用情况和利用障碍。
在一个时间点,在一次常规的门诊就诊中,对等候肝移植的候选者(N=120)进行评估。
参与者报告了中重度抑郁(19.2%)、焦虑(26.7%)和创伤后应激障碍(23.3%)。43%的人在最近接受过某种形式的心理健康治疗,并且存在一系列获取心理健康服务的障碍。在接受结构诊断评估的 39 名参与者中,当前(51.3%)和过去(82.1%)精神障碍的患病率很高。抑郁、焦虑和创伤后应激障碍量表得分升高与健康相关生活质量显著下降相关,但与精神卫生服务利用无差异相关。
有相当数量的终末期肝病患者可以从干预中受益,但目前尚未得到治疗。许多患者认为不需要接受服务,这可能是因为缺乏对心理健康治疗益处的了解或认识。未来的研究应确定针对这一弱势群体的最佳治疗和服务提供方法。