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布加综合征与食管贲门失弛缓症：未被识别的侵犯多个器官的肝内胆管癌

Budd-Chiari Syndrome and Esophageal Achalasia: Unrecognized Intrahepatic Cholangiocarcinoma Invading Multiple Organs.

作者信息

Kakisaka Keisuke, Endo Kei, Sugimoto Ryo, Ishida Kazuyuki, Sugai Tamotsu, Takikawa Yasuhiro

机构信息

Division of Hepatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Japan.

Department of Molecular Diagnostic Pathology, Iwate Medical University School of Medicine, Japan.

出版信息

Intern Med. 2018 Aug 1;57(15):2197-2201. doi: 10.2169/internalmedicine.0448-17. Epub 2018 Mar 9.

DOI:10.2169/internalmedicine.0448-17
PMID:29526953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6120825/
Abstract

Intrahepatic cholangiocarcinoma (ICC) is the second-most common primary liver cancer, although its occurrence is relatively rare. Budd-Chiari syndrome (BCS) is characterized by outflow obstruction from the liver, with hepatocellular carcinoma being the most common cause of malignant BCS. In this case report, we describe the occurrence of an unrecognized ICC that induced BCS and esophageal achalasia.

摘要

肝内胆管癌（ICC）是第二常见的原发性肝癌，尽管其发病率相对较低。布加综合征（BCS）的特征是肝脏流出道梗阻，肝细胞癌是恶性BCS最常见的原因。在本病例报告中，我们描述了一例未被识别的ICC导致BCS和食管贲门失弛缓症的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/665e/6120825/e3a3d6dc501c/1349-7235-57-2197-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/665e/6120825/23f753e164ee/1349-7235-57-2197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/665e/6120825/e3a3d6dc501c/1349-7235-57-2197-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/665e/6120825/23f753e164ee/1349-7235-57-2197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/665e/6120825/e3a3d6dc501c/1349-7235-57-2197-g002.jpg

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Budd-Chiari Syndrome and Esophageal Achalasia: Unrecognized Intrahepatic Cholangiocarcinoma Invading Multiple Organs.布加综合征与食管贲门失弛缓症：未被识别的侵犯多个器官的肝内胆管癌
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本文引用的文献

1
Cholangiocarcinoma - evolving concepts and therapeutic strategies.胆管癌——不断演变的概念与治疗策略
Nat Rev Clin Oncol. 2018 Feb;15(2):95-111. doi: 10.1038/nrclinonc.2017.157. Epub 2017 Oct 10.
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Targeting cholangiocarcinoma.胆管癌靶向治疗。
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Diagnostic features of malignancy-associated pseudoachalasia.恶性肿瘤相关假性贲门失弛缓症的诊断特征。
Aliment Pharmacol Ther. 2017 Jun;45(11):1449-1458. doi: 10.1111/apt.14057. Epub 2017 Apr 6.
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Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA).专家共识文件：胆管癌：来自欧洲胆管癌研究网络（ENS-CCA）的当前知识和未来展望共识声明。
Nat Rev Gastroenterol Hepatol. 2016 May;13(5):261-80. doi: 10.1038/nrgastro.2016.51. Epub 2016 Apr 20.
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Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma.肝内胆管癌诊断和管理指南
J Hepatol. 2014 Jun;60(6):1268-89. doi: 10.1016/j.jhep.2014.01.021. Epub 2014 Mar 27.
6
Pathogenesis, diagnosis, and management of cholangiocarcinoma.胆管癌的发病机制、诊断和治疗。
Gastroenterology. 2013 Dec;145(6):1215-29. doi: 10.1053/j.gastro.2013.10.013. Epub 2013 Oct 15.
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Achalasia.贲门失弛缓症。
Lancet. 2014 Jan 4;383(9911):83-93. doi: 10.1016/S0140-6736(13)60651-0. Epub 2013 Jul 17.
8
An unusual cause of pseudoachalasia: the Alport syndrome-diffuse leiomyomatosis association.一种不常见的假性贲门失弛缓症病因：Alport 综合征-弥漫性平滑肌瘤病相关性。
Eur J Gastroenterol Hepatol. 2013 Nov;25(11):1352-7. doi: 10.1097/MEG.0b013e328361dd17.
9
Good long-term outcome of Budd-Chiari syndrome with a step-wise management.布加综合征的阶梯式管理具有良好的长期疗效。
Hepatology. 2013 May;57(5):1962-8. doi: 10.1002/hep.26306.
10
An update on the diagnosis and management of Budd-Chiari syndrome.布加综合征的诊断和治疗进展。
Expert Rev Gastroenterol Hepatol. 2012 Dec;6(6):731-44. doi: 10.1586/egh.12.56.