Leibniz-Institut für Katalyse e.V. an der Universität Rostock , Albert-Einstein-Straße 29a , Rostock 18059 , Germany.
Lehrstuhl für Theoretische Chemie , Ruhr-Universität Bochum , 44780 Bochum , Germany.
J Am Chem Soc. 2018 Apr 18;140(15):5217-5223. doi: 10.1021/jacs.8b01123. Epub 2018 Apr 9.
A general and selective palladium-catalyzed alkoxycarbonylation of all kinds of alkenes with formic acid (HCOOH, FA) is described. Terminal, di-, tri-, and tetra-substituted including functionalized olefins are converted into linear esters with high yields and regioselectivity. Key-to-success is the use of specific palladium catalysts containing ligands with built-in base, e.g., L5. Comparison experiments demonstrate that the active catalyst system not only facilitates isomerization and carbonylation of alkenes but also promotes the selective decomposition of HCOOH to CO under mild conditions.
本文描述了一种通用的、钯催化的各种烯烃与甲酸（HCOOH，FA）的烷氧基羰基化反应。末端、二取代、三取代和四取代的包括官能化的烯烃都以高产率和区域选择性转化为线性酯。成功的关键是使用含有内置碱的特定钯催化剂，例如 L5。对比实验表明，该活性催化剂体系不仅有利于烯烃的异构化和羰基化，而且还能在温和条件下促进甲酸选择性分解为 CO。
