Mehdizadeh Ali, Rosella Laura, Alavi Afsaneh, Sibbald Gary, Farzanfar Delaram, Hazrati Ali, Vernich Lee, Laporte Audrey, Hu Howard, Bashash Morteza
1 Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
2 Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
J Cutan Med Surg. 2018 May/Jun;22(3):312-317. doi: 10.1177/1203475418763536. Epub 2018 Mar 11.
Hidradenitis suppurativa (HS) is a chronic debilitating disease with long-lasting comorbidities that impose direct and indirect costs on the health care system. However, limited studies have estimated the burden of this disease in Canada, and no population-based studies have previously addressed this condition.
This work describes the characteristics of a population-based HS cohort to address the existing knowledge gap on the burden of HS for the Canadian health care system. This cohort will provide a foundation for further studies about clinical outcomes and risk factors of HS by providing opportunities for merging additional databases.
Data on demographic information, morbidities, relative resource use, and the cost of sectorial services were obtained from the Institute for Clinical Evaluative Sciences (ICES). All residents of Ontario covered by the Ontario Health Insurance Plan (OHIP) between April 1, 2002, and March 31, 2013, who underwent surgery for HS, defined by OHIP billing codes, were included.
A total of 6244 cases were included in the analysis, following quality control procedures. Twice as many females were treated surgically relative to males. The majority of individuals treated were under the age of 64, with more than half having a moderate level of morbidity (according to Resource Utilization Bands defined by the Johns Hopkins Adjusted Clinical Group Classification System).
This cohort study is the first population-based resource about HS in Canada. Administrative population-based databases provide essential information to assess the burden of chronic diseases and identify factors associated with higher cost.
化脓性汗腺炎（HS）是一种慢性致残性疾病，伴有长期的合并症，给医疗保健系统带来直接和间接成本。然而，在加拿大，对这种疾病负担进行估算的研究有限，此前尚无基于人群的研究涉及这一病症。
本研究描述了一个基于人群的HS队列的特征，以填补加拿大医疗保健系统中关于HS负担的现有知识空白。该队列将通过提供合并其他数据库的机会，为进一步研究HS的临床结局和风险因素奠定基础。
人口统计学信息、发病率、相对资源利用情况以及部门服务成本的数据来自临床评估科学研究所（ICES）。纳入2002年4月1日至2013年3月31日期间参加安大略省医疗保险计划（OHIP）且因HS接受手术治疗（根据OHIP计费代码定义）的安大略省所有居民。
经过质量控制程序后，共有6244例病例纳入分析。接受手术治疗的女性人数是男性的两倍。接受治疗的大多数个体年龄在64岁以下，超过一半的个体具有中度发病水平（根据约翰霍普金斯调整临床组分类系统定义的资源利用分组）。
这项队列研究是加拿大首个关于HS的基于人群的资源研究。基于人群的行政数据库为评估慢性病负担和识别与高成本相关的因素提供了重要信息。
