Departments of Medicine and Global Health, University of Washington, Seattle, WA.
Sex Transm Dis. 2018 Sep;45(9S Suppl 1):S7-S9. doi: 10.1097/OLQ.0000000000000830.
The first session at the 2016 Syphilis Summit provided an opportunity for laboratory researchers and clinicians to comment on gaps in biomedical knowledge and technologies. Predominant themes in the presentations and discussion included the need for optimization of existing diagnostic tests, commercial availability, and Food and Drug Administration approval of nucleic acid amplification tests for primary and secondary syphilis, development of sensitive and specific new blood tests for diagnosis of active (vs treated) syphilis infection, clarification of the best measures for adequacy of response to treatment, continued study of complications of syphilis, including neurosyphilis and ocular syphilis, and development of a safe and effective vaccine that will protect against transmission and complications of disseminated infection (including congenital and neurosyphilis). Renewed and sustained support of biomedical syphilis research and an influx of talent could move the needle in the fight against this reemerging ancient disease.
2016 年梅毒峰会的首场会议为实验室研究人员和临床医生提供了一个机会，让他们对生物医学知识和技术方面的差距发表意见。演讲和讨论的主要主题包括需要优化现有的诊断检测、商业可用性，以及食品和药物管理局对原发性和继发性梅毒的核酸扩增检测的批准，开发用于诊断活动性（与治疗后）梅毒感染的敏感和特异性新血液检测，澄清治疗反应充分性的最佳措施，继续研究梅毒的并发症，包括神经梅毒和眼梅毒，以及开发一种安全有效的疫苗，以预防传播和播散性感染（包括先天性和神经梅毒）的并发症。对生物医学梅毒研究的持续和持续支持，以及人才的涌入，可能会推动对抗这种重新出现的古老疾病的努力。
