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最大脑内出血评分预测脑内出血的长期预后。

The max-intracerebral hemorrhage score predicts long-term outcome of intracerebral hemorrhage.

机构信息

Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

China National Clinical Research Center for Neurological Diseases, Beijing, China.

出版信息

CNS Neurosci Ther. 2018 Dec;24(12):1149-1155. doi: 10.1111/cns.12846. Epub 2018 Mar 12.


DOI:10.1111/cns.12846
PMID:29529353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6489715/
Abstract

AIMS: Little is known about the performance of the maximally treated intracerebral hemorrhage (max-ICH) score in predicting unfavorable long-term functional outcome and death in patients with intracerebral hemorrhage (ICH) in China. We aimed to validate the performance of the max-ICH score and compared it with other recognized scores. METHODS: We derived data from the China National Stroke Registry (CNSR). Receiver-operating characteristic (ROC) analysis and Hosmer-Lemeshow test were used to measure the score performance. We compared the performance of max-ICH score with six recognized models, including the ICH score, ICH functional outcome score (ICH-FOS), Essen-ICH score, modified intracerebral hemorrhage (MICH) score, intracerebral hemorrhage grading scale (ICH-GS), and functional outcome (FUNC) score. RESULTS: A total of 2581 patients with spontaneous ICH were enrolled in the study. The max-ICH score was similar or superior to the six existing scores in predicting long-term unfavorable functional outcome after ICH with good discrimination (AUC 0.83, 95% confidence interval [CI] 0.81-0.84) and calibration (Hosmer-Lemeshow P = 0.19). For predicting death, the AUC of max-ICH was 0.81 (95% CI 0.79-0.83). CONCLUSIONS: The easy-to-use max-ICH score is a reliable tool to predict unfavorable long-term (12-month) functional outcome and death after intracerebral hemorrhage in the Chinese population.

摘要

目的:对于中国脑出血(ICH)患者,最大限度治疗的脑出血评分(max-ICH)在预测不良长期功能结局和死亡方面的表现知之甚少。我们旨在验证 max-ICH 评分的表现,并将其与其他公认的评分进行比较。

方法:我们从中国国家卒中登记处(CNSR)中获得数据。使用受试者工作特征(ROC)分析和 Hosmer-Lemeshow 检验来衡量评分表现。我们将 max-ICH 评分与六个公认的模型(包括 ICH 评分、ICH 功能结局评分(ICH-FOS)、Essen-ICH 评分、改良脑出血评分(MICH)、脑出血分级量表(ICH-GS)和功能结局评分(FUNC))的表现进行了比较。

结果:共纳入 2581 例自发性 ICH 患者。max-ICH 评分在预测脑出血后长期不良功能结局方面与六个现有评分相似或更优,具有良好的区分度(AUC 为 0.83,95%置信区间 [CI]为 0.81-0.84)和校准度(Hosmer-Lemeshow P=0.19)。对于预测死亡,max-ICH 的 AUC 为 0.81(95%CI 0.79-0.83)。

结论:易于使用的 max-ICH 评分是一种可靠的工具,可用于预测中国人群脑出血后不良的长期(12 个月)功能结局和死亡。

相似文献

[1]
The max-intracerebral hemorrhage score predicts long-term outcome of intracerebral hemorrhage.

CNS Neurosci Ther. 2018-3-12

[2]
A Comparison of the Intracerebral Hemorrhage Score and the Acute Physiology and Chronic Health Evaluation II Score for 30-Day Mortality Prediction in Spontaneous Intracerebral Hemorrhage.

J Stroke Cerebrovasc Dis. 2017-11

[3]
Severity assessment in maximally treated ICH patients: The max-ICH score.

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[4]
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J Stroke Cerebrovasc Dis. 2017-5

[5]
A novel risk score to predict 1-year functional outcome after intracerebral hemorrhage and comparison with existing scores.

Crit Care. 2013-11-29

[6]
Multicenter Validation of the max-ICH Score in Intracerebral Hemorrhage.

Ann Neurol. 2021-3

[7]
Prognostic value of ICH score and ICH-GS score in Chinese intracerebral hemorrhage patients: analysis from the China National Stroke Registry (CNSR).

PLoS One. 2013-10-16

[8]
Validation of Prognostic Models to Predict Early Mortality in Spontaneous Intracerebral Hemorrhage: A Cross-Sectional Evaluation of a Singapore Stroke Database.

World Neurosurg. 2018-1

[9]
Assessment and comparison of the max-ICH score and ICH score by external validation.

Neurology. 2018-8-1

[10]
Risk score to predict hospital-acquired pneumonia after spontaneous intracerebral hemorrhage.

Stroke. 2014-9

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Acta Neurol Belg. 2024-12

[3]
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[4]
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Neurocrit Care. 2024-4

[5]
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J Cereb Blood Flow Metab. 2024-1

[6]
Increased serum fibroblast growth factor 21 levels are associated with adverse clinical outcomes after intracerebral hemorrhage.

Front Neurosci. 2023-5-5

[7]
Development and internal validation of a clinical risk score for in-hospital mortality after stroke: a single-centre retrospective cohort study in Northwest Ethiopia.

BMJ Open. 2023-3-28

[8]
Comparison of outcome prediction models post-stroke for a population-based registry with clinical variables collected at admission . discharge.

Vessel Plus. 2021

[9]
Lithium attenuates blood-brain barrier damage and brain edema following intracerebral hemorrhage via an endothelial Wnt/β-catenin signaling-dependent mechanism in mice.

CNS Neurosci Ther. 2022-6

[10]
Minimally invasive surgery and transsulcal parafascicular approach in the evacuation of intracerebral haemorrhage.

Stroke Vasc Neurol. 2019-9-26

本文引用的文献

[1]
Safety and efficacy of stereotactic aspiration with fibrinolysis for deep-seated spontaneous intracerebral hemorrhages: A single-center experience.

Medicina (Kaunas). 2017-12

[2]
Palliative Care for Hospitalized Patients With Stroke: Results From the 2010 to 2012 National Inpatient Sample.

Stroke. 2017-9

[3]
Direct oral anticoagulant- vs vitamin K antagonist-related nontraumatic intracerebral hemorrhage.

Neurology. 2017-9-12

[4]
Assessment of the interaction of age and sex on 90-day outcome after intracerebral hemorrhage.

Neurology. 2017-9-5

[5]
Functional Improvement Among Intracerebral Hemorrhage (ICH) Survivors up to 12 Months Post-injury.

Neurocrit Care. 2017-12

[6]
Severity assessment in maximally treated ICH patients: The max-ICH score.

Neurology. 2017-7-5

[7]
Rapid transitions in the epidemiology of stroke and its risk factors in China from 2002 to 2013.

Neurology. 2017-7-4

[8]
Intracerebral hemorrhage location and outcome among INTERACT2 participants.

Neurology. 2017-4-11

[9]
Incident Cerebral Microbleeds in a Cohort of Intracerebral Hemorrhage.

Stroke. 2016-3

[10]
Cause-specific mortality for 240 causes in China during 1990-2013: a systematic subnational analysis for the Global Burden of Disease Study 2013.

Lancet. 2015-10-26

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