Scieux C, Colimon R, Bianchi A, Felten A, Perol Y
Presse Med. 1987 Apr 25;16(15):715-8.
Antibodies to Chlamydia were assayed by complement fixation (CF) and inclusion indirect immunofluorescence (IFI) in sera collected from 379 patients with salpingitis: 30.3% of the patients had total and IgM antibodies at IFI and CF antibodies (profile I); 26.6% of the patients had total and IgM antibodies at IFI without CF antibodies (profile II); 31.6% of the patients had only total antibodies at IFI without specific IgM and without CF antibodies (profile III); 11.3% of the patients were Chlamydia antibody negative (profile IV). In the control group of 50 pregnant women apparently non infected, the profile distribution was 2% profile I, 8% profile II, 38% profile III, and 54% profile IV. Detection of IgM antibodies to Chlamydia trachomatis in 57% of patients with salpingitis, taking only one specimen, suggested recent or active chlamydial infection. CF antibodies indicated diffuse infection. Total antibodies correlated well with IgG antibodies detected by ELISA. Their finding was by no means diagnosis for Chlamydia being the cause of tubal infection, although titers observed in salpingitis patients were higher than in controls.
采用补体结合试验（CF）和包涵体间接免疫荧光法（IFI）检测了379例输卵管炎患者血清中的衣原体抗体：30.3%的患者在IFI检测中有总抗体和IgM抗体，且有CF抗体（I型）；26.6%的患者在IFI检测中有总抗体和IgM抗体，但无CF抗体（II型）；31.6%的患者在IFI检测中仅有总抗体，无特异性IgM且无CF抗体（III型）；11.3%的患者衣原体抗体阴性（IV型）。在50名明显未感染的孕妇组成的对照组中，各型分布情况为：I型2%，II型8%，III型38%，IV型54%。对57%的输卵管炎患者仅采集一份标本检测沙眼衣原体IgM抗体，提示近期或活动性衣原体感染。CF抗体提示弥漫性感染。总抗体与ELISA检测的IgG抗体相关性良好。尽管输卵管炎患者中观察到的抗体滴度高于对照组，但这些抗体的检测结果绝不能确诊衣原体是输卵管感染的病因。
