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甲状腺细针穿刺细胞学检查结果的贝塞斯达分类:机构经验及文献综述

Classification of thyroid fine-needle aspiration cytology into Bethesda categories: An institutional experience and review of the literature.

作者信息

Alshaikh Safa, Harb Zainab, Aljufairi Eman, Almahari S Ali

机构信息

Address: Department of Pathology, Salmanyia Medical Complex, Manama, Bahrain.

出版信息

Cytojournal. 2018 Feb 16;15:4. doi: 10.4103/cytojournal.cytojournal_32_17. eCollection 2018.

Abstract

BACKGROUND

Fine-needle aspiration cytology (FNAC) of thyroid is the initial screening test for thyroid nodules. The Bethesda system classifies thyroid FNAC into six categories. Each category is linked to a malignancy risk and has a recommended clinical management. The aim of this study is to analyze the thyroid cytology smears by Bethesda system and to correlate the diagnosis of cytopathology with histopathology, whenever surgery was done.

MATERIALS AND METHODS

This study presents our experience with the Bethesda system in 681 thyroid FNAs from 632 patients in the period between January 2013 and December 2016.

RESULTS

Categories were as follows: 10.1% were Category I (nondiagnostic), 68.8% Category II (benign), 12.4% were Category III (atypia of undetermined significance), 2.9% were Category IV (suspicious for follicular neoplasm), 2.6% were Category V (suspicious for malignancy), and 4.1% were Category VI (malignant). Surgery was done on 126 nodules from 119 patients with an overall rate of malignancy of 27.8% (35/126 nodules).

CONCLUSION

The Bethesda System for Reporting Thyroid Cytopathology proved to be an excellent reporting system.

摘要

背景

甲状腺细针穿刺细胞学检查(FNAC)是甲状腺结节的初始筛查试验。贝塞斯达系统将甲状腺FNAC分为六类。每一类都与恶性风险相关,并具有推荐的临床管理方法。本研究的目的是通过贝塞斯达系统分析甲状腺细胞学涂片,并在进行手术时将细胞病理学诊断与组织病理学进行关联。

材料与方法

本研究介绍了我们在2013年1月至2016年12月期间对632例患者的681次甲状腺细针穿刺活检应用贝塞斯达系统的经验。

结果

分类如下:I类(无法诊断)占10.1%,II类(良性)占68.8%,III类(意义不明确的非典型病变)占12.4%,IV类(可疑滤泡性肿瘤)占2.9%,V类(可疑恶性肿瘤)占2.6%,VI类(恶性)占4.1%。对119例患者的126个结节进行了手术,总体恶性率为27.8%(35/126个结节)。

结论

甲状腺细胞病理学报告的贝塞斯达系统被证明是一个优秀的报告系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2af7/5841007/2bfdc1c9f1ac/CJ-15-4-g005.jpg

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