Melo-Uribe Mario Alexander, Sanabria Álvaro, Romero-Rojas Alfredo, Pérez Gabriel, Vargas Elga Johanna, Abaúnza María Claudia, Gutiérrez Víctor
Department of Surgical Pathology, Universidad de La Sabana, Colombia.
Department of Surgery, Universidad de Antioquia-Hospital Pablo Tobón Uribe, Colombia.
J Cytol. 2015 Jan-Mar;32(1):12-6. doi: 10.4103/0970-9371.155224.
To determine the correlation between the results of thyroid fine-needle aspirations interpreted using the Bethesda system and final histopathological reports for patients at an oncology hospital (OH) and non-oncology hospitals (NOHs).
A retrospective, cross-sectional, descriptive study was performed to compare the cytology and histopathology results for patients with thyroid nodules in three Colombian hospitals. The final correlation of diagnoses between the two methods is reported. In Colombia, the health system provides the existence of general care hospitals and hospitals specializing in care of patients with cancer.
A total of 196 reports were reviewed, of which 53% were from OH and 47% were from NOHs. A greater proportion of category V (37.5%) was diagnosed at the OH, whereas NOHs diagnosed a greater proportion of category II (42.3%). The global correlation between diagnoses made using cytology and histopathology was 93.3% for categories V and VI (based on the final malignant diagnosis) and 86.9% for benign category II. Significant differences between institution types were observed when category IV and V and malignant histopathology were compared (56.3% OH vs. 23.5% NOH; P = 0.05 for category IV, 97.4% OH vs. 82.3% NOH; P = 0.03 for category V), while no significant difference between institution types was observed when category II and final benign diagnosis were compared (P = 0.6).
The Bethesda system for thyroid cytology correlates adequately with final histopathological diagnosis in Colombia. Significant differences were identified in the diagnostic correlation for malignant lesions between the OH and NOHs in categories IV and V caused by selection bias of the population.
确定在一家肿瘤医院（OH）和非肿瘤医院（NOHs）中，使用贝塞斯达系统解读的甲状腺细针穿刺结果与患者最终组织病理学报告之间的相关性。
进行了一项回顾性、横断面描述性研究，以比较三家哥伦比亚医院甲状腺结节患者的细胞学和组织病理学结果。报告了两种方法之间诊断的最终相关性。在哥伦比亚，卫生系统提供综合医院和专门治疗癌症患者的医院。
共审查了196份报告，其中53%来自OH，47%来自NOHs。OH诊断出更高比例的V类（37.5%），而NOHs诊断出更高比例的II类（42.3%）。对于V类和VI类（基于最终恶性诊断），细胞学和组织病理学诊断之间的总体相关性为93.3%，良性II类为86.9%。比较IV类和V类以及恶性组织病理学时，观察到机构类型之间存在显著差异（IV类：OH为56.3%，NOHs为23.5%；P = 0.05；V类：OH为97.4%，NOHs为82.3%；P = 0.03），而比较II类和最终良性诊断时，未观察到机构类型之间的显著差异（P = 0.6）。
在哥伦比亚，甲状腺细胞学的贝塞斯达系统与最终组织病理学诊断具有充分的相关性。由于人群选择偏倚，OH和NOHs在IV类和V类恶性病变的诊断相关性方面存在显著差异。
