Kondoff Slavomir, Drenchev Atanas, Lotti Torello, Wollina Uwe, Lozev Ilia, Pidakev Ivan, Terziev Ivan, Grigorov Yavor, Gianfaldoni Serena, Tchernev Georgi
Okrajna Bolnica - Neurosurgery Sofia, Sofia, Bulgaria.
University Hospital Saint Anna - Neurosurgery Sofia, Sofia, Bulgaria.
Open Access Maced J Med Sci. 2018 Feb 14;6(2):372-375. doi: 10.3889/oamjms.2018.101. eCollection 2018 Feb 15.
Basal cell carcinomas (BCC) located in the sun-exposed regions are a serious therapeutic challenge. Therefore early diagnosis and adequate therapy should be of a high priority for every dermatologic surgeon.
We are presenting a patient with multiple BCCs, located on the area of the scalp, who had been treated several years ago with electrocautery and curettage after histopathological verification. However, the last few years the tumours have advanced, infiltrating firstly the tabula external and a year later the tabula interna of the cranium. A computed -tomography (CT) imaging and radiography of the skull were performed to reveal the definite tumour localisation, needed for planning an one - step surgical intervention. Both of the instrumental examinations confirmed the existence of osteolytic tumour lesions. Craniotomy with precise removal of the BCCs infiltrating the cranial bone in all of its thickness was performed. Partial resection of dura mater was also performed also because intraoperative findings established the involvement of the dura. Histopathological verification revealed bone and dural invasion with clean resection margins. The bone defect was recovered with hydroxyapatite cement. Reconstruction as the shape of the skull was carefully modified and adapted to its initial size and form. Layered closure of the skin and soft tissues were performed after the complete removal of the BCCs. The postoperative period had no serious complications.
Precisely managed therapy of BCC is curative in most of the cases as it ensures good prognosis for the patient.
位于阳光暴露部位的基底细胞癌(BCC)是一项严峻的治疗挑战。因此,早期诊断和恰当治疗应是每位皮肤科外科医生的首要任务。
我们报告一名头皮部位患有多发性基底细胞癌的患者,数年前经组织病理学确诊后接受了电灼和刮除术治疗。然而,在过去几年中肿瘤进展,首先侵犯颅骨外板,一年后侵犯颅骨内板。进行了计算机断层扫描(CT)成像和颅骨X线摄影,以明确肿瘤定位,这对于规划一步式手术干预是必要的。两项检查均证实存在溶骨性肿瘤病变。实施了开颅手术,精确切除全层浸润颅骨的基底细胞癌。由于术中发现硬脑膜受累,还进行了硬脑膜部分切除术。组织病理学检查证实骨和硬脑膜受侵,切缘干净。用羟基磷灰石水泥修复骨缺损。仔细调整颅骨重建的形状,使其恢复到初始大小和形态。在完全切除基底细胞癌后,分层缝合皮肤和软组织。术后无严重并发症。
精确管理的基底细胞癌治疗在大多数情况下具有治愈性,因为它能确保患者有良好的预后。