二羟基丙酮：对一种重要生物制品的最新见解。
Dihydroxyacetone: An Updated Insight into an Important Bioproduct.
作者信息
Ciriminna Rosaria, Fidalgo Alexandra, Ilharco Laura M, Pagliaro Mario
机构信息
Istituto per lo Studio dei Materiali Nanostrutturati, CN Rvia U. La Malfa 153 90146 Palermo Italy.
Centro de Química-Física Molecular and IN-Institute of Nanoscience and Nanotechnology Instituto Superior Técnico, Universidade de Lisboa Av. Rovisco Pais 1 1049-001 Lisboa Portugal.
出版信息
ChemistryOpen. 2018 Mar 6;7(3):233-236. doi: 10.1002/open.201700201. eCollection 2018 Mar.
Abstract
Currently obtained from glycerol through microbial fermentation, the demand of 1,3-dihydroxyacetone (DHA) has significantly grown during the course of the last decade, driven by the consumer passion for a tan and increasing awareness of UV photodamage to the skin caused by prolonged exposure to the sun. We provide an updated bioeconomy perspective into a valued bioproduct (DHA), whose supply and production from glycerol, we argue in this study, will rapidly expand and diversify, with important global health benefits.
摘要
目前，1,3 - 二羟基丙酮（DHA）是通过微生物发酵从甘油中获取的。在过去十年中，由于消费者对晒黑的热衷以及对长期暴露于阳光下导致皮肤紫外线光损伤的认识不断提高，DHA的需求显著增长。我们从生物经济的角度对一种有价值的生物产品（DHA）进行了更新阐述。在本研究中，我们认为，DHA由甘油供应和生产的情况将迅速扩展并多样化，从而为全球健康带来重要益处。
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本文引用的文献
1
Dihydroxyacetone induces G2/M arrest and apoptotic cell death in A375P melanoma cells.
Environ Toxicol. 2018 Mar;33(3):333-342. doi: 10.1002/tox.22520. Epub 2017 Nov 29.
2
Dihydroxyacetone and sunless tanning: Knowledge, myths, and current understanding.
J Am Acad Dermatol. 2017 Nov;77(5):991-992. doi: 10.1016/j.jaad.2017.04.1117.
3
[Self-tanning and sunless tanning products].
Ann Dermatol Venereol. 2017 Oct;144(10):638-644. doi: 10.1016/j.annder.2017.03.021. Epub 2017 Aug 18.
4
Food Processing and Maillard Reaction Products: Effect on Human Health and Nutrition.
Int J Food Sci. 2015;2015:526762. doi: 10.1155/2015/526762. Epub 2015 Jan 8.
5
Disruption of the membrane-bound alcohol dehydrogenase-encoding gene improved glycerol use and dihydroxyacetone productivity in Gluconobacter oxydans.
Biosci Biotechnol Biochem. 2010;74(7):1391-5. doi: 10.1271/bbb.100068. Epub 2010 Jul 7.
6
Do melanoidins induced by topical 9% dihydroxyacetone sunless tanning spray inhibit vitamin d production? A pilot study.
Photochem Photobiol. 2009 Sep-Oct;85(5):1265-6. doi: 10.1111/j.1751-1097.2009.00574.x. Epub 2009 May 28.
7
Dihydroxyacetone: a safe camouflaging option in vitiligo.
Int J Dermatol. 2008 Apr;47(4):402-6. doi: 10.1111/j.1365-4632.2008.03356.x.
8
UV-generated free radicals (FR) in skin: their prevention by sunscreens and their induction by self-tanning agents.
Spectrochim Acta A Mol Biomol Spectrosc. 2008 May;69(5):1423-8. doi: 10.1016/j.saa.2007.09.029. Epub 2007 Oct 10.
9
Dihydroxyacetone, the active browning ingredient in sunless tanning lotions, induces DNA damage, cell-cycle block and apoptosis in cultured HaCaT keratinocytes.
Mutat Res. 2004 Jun 13;560(2):173-86. doi: 10.1016/j.mrgentox.2004.03.002.
10
Fate of chemicals in skin after dermal application: does the in vitro skin reservoir affect the estimate of systemic absorption?
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