Gold Michael H, Coleman W Patrick, Coleman William, Weiss Robert
a Tennessee Clinical Research Center , Nashville , TN , USA.
b Coleman Center for Cosmetic Dermatologic Surgery , Metairie , LA , USA.
J Cosmet Laser Ther. 2019;21(1):44-48. doi: 10.1080/14764172.2018.1444778. Epub 2018 Mar 13.
Energy-based cosmetic devices offer an in-office treatment option, with minimal downtime, to non-invasively remove unwanted fat. We evaluated focused, pulsed ultrasound treatment to randomized flanks, compared to corresponding non-treated contralateral flanks.
Subjects were enrolled at three sites for a series of focused ultrasound treatments to a single flank, with the contralateral flank remaining untreated throughout the study. Success criteria included measureable fat thickness reduction on ultrasound imaging in the treated areas at 16 weeks after the final treatment session, and correct identification of the post-treatment photo and treated flank in at least 80% of evaluated images, as assessed by two blinded evaluators.
The post-treatment flank photo and treated flank side were correctly identified in 82% and 93% of cases, respectively. All study subjects demonstrated significant fat reduction in their treated area, as measured by ultrasound and skin caliper. Subjects expressed a high satisfaction from treatment outcomes. There were no complications with treatment.
A series of three ultrasound treatments resulted in significant fat reduction in treated flanks. Although treatment results are more modest than with liposuction, non-invasive ultrasound treatment may provide an attractive alternative for patients seeking an in-office, nonsurgical procedure for fat reduction.
基于能量的美容设备提供了一种门诊治疗选择，停机时间最短，可无创去除多余脂肪。我们评估了聚焦脉冲超声治疗一侧随机选择的侧腹，并与相应未治疗的对侧侧腹进行比较。
在三个地点招募受试者，对一侧侧腹进行一系列聚焦超声治疗，在整个研究过程中对侧侧腹不进行治疗。成功标准包括在最后一次治疗后16周时，治疗区域超声成像显示可测量的脂肪厚度减少，以及由两名盲法评估者评估，在至少80%的评估图像中正确识别治疗后的照片和治疗侧腹。
分别在82%和93%的病例中正确识别出治疗后的侧腹照片和治疗侧腹。通过超声和皮肤卡尺测量，所有研究受试者治疗区域的脂肪均显著减少。受试者对治疗结果表示高度满意。治疗无并发症。
一系列三次超声治疗可使治疗侧腹的脂肪显著减少。尽管治疗效果比吸脂术要差一些，但无创超声治疗可能为寻求门诊非手术减脂程序的患者提供一个有吸引力的选择。
