Kawai Y, Ohhashi T
Experientia. 1987 May 15;43(5):568-70. doi: 10.1007/BF02143587.
Effects of atrial natriuretic factor (ANF) on monkey, rabbit and dog internal carotid arteries were investigated. ANF caused a concentration-dependent relaxation in arterial strips submaximally precontracted with noradrenaline, 5-hydroxytryptamine, or high-potassium solution (10-30 mM). The response was greatest in the monkey arteries and least in the dog arteries. These results suggest that there is a marked species difference in the ANF-induced relaxation of the internal carotid arteries.
研究了心房利钠因子（ANF）对猴、兔和犬颈内动脉的作用。ANF能使预先用去甲肾上腺素、5-羟色胺或高钾溶液（10 - 30 mM）进行次最大收缩的动脉条产生浓度依赖性舒张。该反应在猴动脉中最大，在犬动脉中最小。这些结果表明，ANF诱导的颈内动脉舒张存在明显的种属差异。
