Ko Eugene M, McHugh Jonathan B
School of Dentistry, University of Michigan, 1011 N University Ave, Ann Arbor, MI, 48109, USA.
Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
Head Neck Pathol. 2018 Dec;12(4):529-533. doi: 10.1007/s12105-018-0907-5. Epub 2018 Mar 13.
This clinicopathologic study of primary oral leiomyosarcoma of the buccal mucosa involves a literature review of 15 cases with the addition of our report of a case. The demographic details, tumor size, treatment and outcome are documented for all the cases. In addition, this review examines the histologic features of leiomyosarcoma while noting that differentiation from other spindle cell tumors can be challenging, underscoring the necessity of an immunohistochemical work up for an accurate diagnosis. The unpredictability of the clinical behavior of these aggressive tumors requires, at the very least, wide local surgical excision and prolonged follow up.
这项关于颊黏膜原发性口腔平滑肌肉瘤的临床病理研究包括对15例病例的文献综述，并附上我们报告的1例病例。记录了所有病例的人口统计学细节、肿瘤大小、治疗方法和结果。此外，本综述研究了平滑肌肉瘤的组织学特征，同时指出与其他梭形细胞瘤的鉴别可能具有挑战性，强调了进行免疫组化检查以准确诊断的必要性。这些侵袭性肿瘤临床行为的不可预测性至少需要广泛的局部手术切除和长期随访。
