Long Keyi, Cai Lei, He Lin
Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Collaborative Innovation Center for Genetics and Development, Shanghai Jiao Tong University, Shanghai, 200240, China.
Methods Mol Biol. 2018;1754:1-13. doi: 10.1007/978-1-4939-7717-8_1.
Among various biological data, DNA sequence is doubtlessly a fundamental datum. By obtaining particular DNA sequence data and analyzing, biologists get to understand life science more precisely. This chapter is an overview of DNA sequencing technology and its data analysis methods, providing information about DNA sequencing, several different methods, and tools applied in data analysis. Both advantages and disadvantages are discussed.
在各种生物数据中，DNA序列无疑是一项基础数据。通过获取特定的DNA序列数据并进行分析，生物学家能够更精确地理解生命科学。本章概述了DNA测序技术及其数据分析方法，介绍了DNA测序、几种不同的方法以及数据分析中应用的工具。同时讨论了其优缺点。
