Schmidt C, Schmitt J, Scheffmann M
J Mal Vasc. 1987;12(2):144-9.
Fifty-five patients with unilateral deep thrombophlebitis of lower limbs were followed up for a mean duration of 15 months after the acute onset (178 series of plethysmographic measurements). Statistical analysis showed excellent reproducibility of venous plethysmographic parameters (capacitance and emptying rate) both on healthy and affected sides. Best values for emptying were observed after thrombolysis in situ but the difference was not significant in relation to heparin therapy. The application of a filter or a caval clip provoked bilateral, symmetrical slowing of venous emptying during the first few months, with a tendency for normal values to be restored after one year. The ratio of emptying rates (affected side/healthy side) was less than 60% if venous obstruction persisted with or without deep devalvulation. A lack of significant correlation existed between clinical course and plethysmographic parameters, 15 months after the initial episode, capacitance and venous emptying remaining pathologic allowing retrospective diagnosis. A longer follow up (5 to 10 years) with the same protocol is projected.
55例单侧下肢深部血栓性静脉炎患者在急性发作后平均随访15个月(共进行178次体积描记测量)。统计分析表明,静脉体积描记参数(容量和排空率)在健侧和患侧均具有良好的可重复性。原位溶栓后观察到最佳排空值,但与肝素治疗相比差异不显著。放置滤网或腔静脉夹在最初几个月会引起双侧、对称性的静脉排空减慢,一年后有恢复正常的趋势。如果存在静脉阻塞且伴有或不伴有深静脉瓣功能不全,排空率(患侧/健侧)低于60%。在初次发作15个月后,临床病程与体积描记参数之间缺乏显著相关性,容量和静脉排空仍为病理性,可进行回顾性诊断。计划采用相同方案进行更长时间的随访(5至10年)。