Bachet P, Ninet J, Guillaume A, Fournet D, Pasquier J
J Mal Vasc. 1987;12(2):168-74.
A prospective study, now pursued, has the aim of determining anatomical features (permeability of deep venous trunks and/or development of a collateral venous circulation) related to improvement in plethysmographic indices and comparing these with phlebographic data. Twelve patients have been investigated by occlusive plethysmography and bilateral phlebography of lower limbs on the day of diagnosis, after 10 days of heparin therapy and after 6 months of antivitamin K anticoagulant treatment started on the 11th day. Whereas a progressive improvement in plethysmographic indices and phlebographic scores exists during the course of treatment, no correlation has been observed between plethysmographic indices and degree of phlebographic obstruction. This suggests that the emptying rate indices cannot be considered as an absolute criterion for the decision to discontinue anticoagulant therapy.
目前正在进行的一项前瞻性研究旨在确定与体积描记指数改善相关的解剖学特征(深静脉主干的通透性和/或侧支静脉循环的发展),并将这些特征与静脉造影数据进行比较。在诊断当天、肝素治疗10天后以及从第11天开始进行6个月的抗维生素K抗凝治疗后,对12例患者进行了下肢闭塞体积描记法和双侧静脉造影检查。尽管在治疗过程中体积描记指数和静脉造影评分有逐步改善,但未观察到体积描记指数与静脉造影阻塞程度之间的相关性。这表明排空率指数不能被视为决定停止抗凝治疗的绝对标准。