Daniel Michael A, Van Dyke Thomas E
J Periodontol. 1996 Oct;67 Suppl 10S:1070-1075. doi: 10.1902/jop.1996.67.10s.1070.
A review of phagocytic cells-polymorphonuclear leukocytes and monocytes-in the inflammatory process is presented. Examples of phagocyte defect-related pathology serve as a framework for understanding the role of these cells in periodontal infection. The role of alterations in neutrophil function in localized juvenile periodontitis is presented as a model system for understanding periodontal pathology as a result of host-related functional abnormalities. Two topical alternative hypotheses for periodontal breakdown are presented in which. macrophage control of the chronic lesion is altered by an absence of T cells or the influence of bacterial superantigens. J Periodontol 1996;67:1070-1075.
本文综述了吞噬细胞——多形核白细胞和单核细胞——在炎症过程中的作用。与吞噬细胞缺陷相关的病理学实例为理解这些细胞在牙周感染中的作用提供了一个框架。中性粒细胞功能改变在局限性青少年牙周炎中的作用作为一个模型系统，用于理解由于宿主相关功能异常导致的牙周病理学。本文还提出了两种关于牙周破坏的局部替代假说，即巨噬细胞对慢性病变的控制因T细胞缺失或细菌超抗原的影响而改变。《牙周病学杂志》1996年；67:1070 - 1075。
