Mandart G, Puttemans M, Struelens M, Pirart J
Presse Med. 1986 Nov 29;15(42):2101-3.
Surgical procedure and anaesthesia commonly induce severe diabetes maladjustment. In these circumstances, optimal insulin administration is crucial and has been shown to prevent hyperglycaemia which is mostly due to insulin-counteracting hormones. We report the results obtained in 12 diabetic patients treated with a new method during various surgical procedures. The method consists of constant rate intravenous administration of a 5% glucose solution associated with intravenous insulin infusion delivered by an electric syringe at the rate of 1/2 U of insulin per hour for each glycaemic variation of 50 mg/dl. With this simple method, blood glucose concentrations remain close to physiological levels, and no hypoglycaemia occurs.
外科手术和麻醉通常会引发严重的糖尿病失调。在这些情况下,优化胰岛素给药至关重要,并且已证明可预防主要由胰岛素拮抗激素引起的高血糖症。我们报告了12名糖尿病患者在各种外科手术期间采用一种新方法治疗所获得的结果。该方法包括以恒定速率静脉输注5%葡萄糖溶液,并通过电动注射器以每50mg/dl血糖变化每小时1/2单位胰岛素的速率静脉输注胰岛素。通过这种简单的方法,血糖浓度可维持在接近生理水平,且不会发生低血糖症。