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孟加拉农村地区主要神经系统疾病的神经流行病学

Neuroepidemiology of major neurological disorders in rural Bengal.

作者信息

Das S K, Sanyal K

机构信息

Department of Neuromedicine, Bangur Institute of Neurology, Calcutta, India.

出版信息

Neurol India. 1996 Apr-Jun;44(2):47-58.

Abstract

A Neuroepidemiological survey was carried at Malda district, 350 Km away from Calcutta; exactly at midpoint between Siliguri and Calcutta on a rural population of 37,286 (M 18,057; F 19,229; 1981 Census) under three Gram Panchayat areas with the help of non-professionals like Gram Panchayat members, ICDS workers, multipurpose health workers and motivated local youths, based on W.H.O. protocol (1981). House to house survey was carried out. Sensitivity reached 90 and Specificity 86. Total 961 individuals with neurological problems were screened and classified according to simple, but well defined criteria. Single disease was seen in 857 patients and 104 patients had double disease. Crude prevalence rate stands at ( 2856.26 per 1,00,000), epilepsy (305 per 1,00,000), vertigo (24.45 per 1,00,000), mental retardation (42.90 per 1,00,000), paralytic poliomyelitis (53.63 per, 1,00,000), movement disorders (26.81 per 1,00,000), spinal cord disorders (21 per 1,00,000), motor neurone disease (2.7 pre 1,00,000), development of speech and language (34 per 1,00,000). Age specific prevalence disease showed progressive increase in rate with advancing age upto 4th decade followed by a slightly decrease plateau upto 60 years of age and then sharp decline. Age and sex specific disease prevalence shows female dominance with maximum cases in 4th decade.

摘要

在距离加尔各答350公里的马尔达地区进行了一项神经流行病学调查;该地区恰好位于西里古里和加尔各答之间的中点,调查对象是三个村潘查亚特地区的37286名农村人口(男性18057人;女性19229人;1981年人口普查数据),调查借助了村潘查亚特成员、综合儿童发展服务计划工作人员、多用途卫生工作者以及积极主动的当地青年等非专业人员,依据世界卫生组织的方案(1981年)进行。逐户进行了调查。灵敏度达到90,特异度达到86。共筛查出961名有神经问题的个体,并根据简单但明确的标准进行了分类。857名患者患单一疾病,104名患者患两种疾病。粗患病率为(每10万人中有2856.26人),癫痫(每10万人中有305人),眩晕(每10万人中有24.45人),智力迟钝(每10万人中有42.90人),麻痹性脊髓灰质炎(每10万人中有53.63人),运动障碍(每10万人中有26.81人),脊髓疾病(每10万人中有21人),运动神经元病(每10万人中有2.7人),言语和语言发育问题(每10万人中有34人)。特定年龄患病率显示,患病率随年龄增长至第四个十年呈逐渐上升趋势,随后在60岁之前略有下降并趋于平稳,然后急剧下降。特定年龄和性别的疾病患病率显示女性占主导,在第四个十年病例数最多。

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